ArticleTherapeutic advances in chronic disease2021
Comparison between 2D radiographic weight-bearing joint space width and 3D MRI non-weight-bearing cartilage thickness measures in the knee using non-weight-bearing 2D and 3D CT as an intermediary.
Article in Therapeutic advances in chronic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Longitudinal 3D quantification of joint space from CT images: Semi-automatic segmentation and feasibility of nnU-Net automation.Osteoarthritis imaging · 2026Article
- High-Fidelity Measurement-Based Detection Values and Roles of Three-Dimensional Joint Space Width in Evaluation of Knee Osteoarthritis.Orthopaedic surgery · 2026Article
- Impact of single-leg versus double-leg weight-bearing radiographs on surgical decision-making in knee osteoarthritis.Acta orthopaedica et traumatologica turcica · 2025Article
- Subchondral bone expansion in advanced knee osteoarthritis: Relation with radiographic severity and role in surgical decision-making.Osteoarthritis and cartilage open · 2024Article
- Prevalence of proximal tibia vara in Indonesian population with knee osteoarthritis.Journal of clinical orthopaedics and trauma · 2022Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
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Abstract
backgroundIn knee osteoarthritis, radiographic joint space width (JSW) is frequently used as a surrogate marker for cartilage thickness; however, longitudinal changes in radiographic JSW have shown poor correlations with those of magnetic resonance imaging (MRI) cartilage thickness. There are fundamental differences between the techniques: radiographic JSW represents two-dimensional (2D), weight-bearing, bone-to-bone distance, while on MRI three-dimensional (3D) non-weight-bearing cartilage thickness is measured. In this exploratory study, computed tomography (CT) was included as a third technique, as it can measure bone-to-bone under non-weight-bearing conditions. The objective was to use CT to compare the impact of weight-bearing
methodsOsteoarthritis patients (
resultsFourteen patients could be analyzed. Cross-sectionally, all comparisons showed moderate to strong significant correlations (R = 0.43-0.81; all
conclusionThe poor correlation between changes in radiographic JSW and MRI cartilage thickness appears primarily to result from the difference in weight-bearing, and less so from measuring bone-to-bone distance
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