ArticleJournal of medical cases2020
Isolated Neutropenia: An Unexplored Side Effect of Amiodarone.
Article in Journal of medical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amiodarone has been widely used for the treatment of various arrhythmias. It is a potent P450 inhibitor leading to interaction with many commonly prescribed drugs. Also, due to its long half-life, lipophilicity, and broad tissue distribution, it can cause a wide range of toxicities. A 62-year-old male with the unknown past medical history presented to the emergency department following a grand mal seizure. The patient initially presented with atrial flutter, which was controlled with beta blockers but was switched to amiodarone after 2 weeks when he developed atrial fibrillation with the rapid ventricular response. Approximately 1 month into his hospital stay, the patient developed severe isolated neutropenia. After ruling out other etiologies, amiodarone was withdrawn. The patient's absolute neutrophil count recovered 3 days after discontinuation of amiodarone.
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