ArticleTherapeutic advances in neurological disorders2021
A novel score for evaluating cerebral aneurysms treated with flow diversion: 4F-flow diversion predictive score.
Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03831672 (Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China), which is not on this map. Cited by 4 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China (PLUS)
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Application of machine learning algorithms to predict and assess factors related to internal carotid siphon aneurysm occlusion treated with flow diversion.Neuroradiology · 2026Article
- Evaluation of flow diverters for cerebral aneurysm therapy: recommendations for imaging analyses in clinical studies, endorsed by ESMINT, ESNR, OCIN, SILAN, SNIS, and WFITN.Journal of neurointerventional surgery · 2025Article
- Imaging of Intracranial Saccular Aneurysms.Stroke (Hoboken, N.J.) · 2023Review
- Incidence and Risk Factors for Acute Transient Contrast-Induced Neurologic Deficit: A Systematic Review With Meta-Analysis.Stroke (Hoboken, N.J.) · 2022Article
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Authors and funding
15 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeAlthough grading scales for angiography outcomes following cerebral aneurysm treatment with flow diversion have been published, physicians have not widely adopted these scales in practice. The aim of this study is to propose and validate a novel Flow diversion Predictive Score (4F-FPS) grading scale based on previously established scales that is simple and reliable.
methodsWe retrospectively analyzed consecutive patients who underwent endovascular treatment for cerebral aneurysms with flow diversion between January 2014 and September 2019. The included patients were randomly divided into the derivation and validation group in a 70/30 ratio, respectively. Aneurysms were classified as incomplete or complete occlusion based on final angiography outcomes. 4F-FPS was derived to predict aneurysm occlusion from multivariate logistic regression analyses in the derivation group and validated with previously published grading scales in the validation group.
resultsOverall, 662 patients [mean age, 53.8 years; 72.5% (480/662) female] with 662 aneurysms treated with the Pipeline
conclusionThe 4F-FPS score is a simple and reliable tool to predict angiography outcome after flow diversion treatment. If widely adopted, it may provide a common language to be used in future reporting of flow diversion results for clinical trials and daily practice. CLINICAL
trial registrationhttp://www.clinicaltrials.gov. Unique identifier: NCT03831672.
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