Evidence map›Paper›PMID 34434211›Full record

ArticleFrontiers in genetics2021

Hearing Loss in Id1

Qingyin Zheng, Tihua Zheng, Aizhen Zhang, Bin Yan, Bo Li, Zhaoqiang Zhang, Yan Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qingyin ZhengDepartment of Otolaryngology - Head and Neck Surgery, Second Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, China.
Tihua ZhengDepartment of Otolaryngology - Head and Neck Surgery, Second Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, China.
Aizhen ZhangSchool of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Bin YanCollege of Special Education, Hearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Bo LiCollege of Special Education, Hearing and Speech Rehabilitation Institute, Binzhou Medical University, Yantai, China.
Zhaoqiang ZhangSchool of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Yan ZhangDepartment of Otolaryngology - Head and Neck Surgery, Second Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, China.

Funding

Deciphering the Usher I protein interactome using a geneticapproachR01DC015111 · NIDCD · CASE WESTERN RESERVE UNIVERSITY · PI ZHENG, QING Y · 2016 to 2020
$1.8M
Identify and Develop Mouse Models for Otitis MediaR21DC005846 · NIDCD · JACKSON LABORATORY · PI ZHENG, QING Y · 2003 to 2005
$562k
NIDCD NIH HHS R01 DC015111NIDCD NIH HHS R21 DC005846
6 · The paper itself

Abstract

Inhibitors of differentiation/DNA binding (Id) proteins are crucial for inner ear development, but whether Id mutations affect middle ear function remains unknown. In this study, we obtained Id1

Indexed as

genetic predispositionhearing lossinflammationmouse modelotitis media

Identifiers

PMID34434211
PMCPMC8381378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.