Evidence map›Paper›PMID 34434088›Full record

ArticleFrontiers in molecular neuroscience2021

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia.

Steven W Bothwell, Daniel Omileke, Rebecca J Hood, Debbie-Gai Pepperall, Sara Azarpeykan, Adjanie Patabendige, Neil J Spratt

Abstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Intracranial pressure is elevated at 24 h post-stroke in mice.Neuroprotection (Chichester, England) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Steven W BothwellThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Daniel OmilekeThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Rebecca J HoodThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Debbie-Gai PepperallThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Sara AzarpeykanThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Adjanie PatabendigeThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.
Neil J SprattThe School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oedema-independent intracranial pressure (ICP) rise peaks 20-22-h post-stroke in rats and may explain early neurological deterioration. Cerebrospinal fluid (CSF) volume changes may be involved. Cranial CSF clearance primarily occurs

Indexed as

cerebrospinal fluidinfarct expansionintracranial pressureischaemialymphaticsneurological deteriorationspinal clearancestroke

Identifiers

PMID34434088
PMCPMC8380845

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.