Evidence map›Paper›PMID 34433907›Full record

ArticleInternational journal of obesity (2005)2021

Association between obesity and hospital mortality in critical COVID-19: a retrospective cohort study.

Guillaume Plourde, Emanuel Fournier-Ross, Hubert Tessier-Grenier, Louis-Antoine Mullie, Michaël Chassé, François Martin Carrier

Open access · bronzeAbstract read
In one paragraph

Article in International journal of obesity (2005), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Guillaume PlourdeDepartment of Medicine, Université de Montréal, Montréal, QC, Canada.ORCID http://orcid.org/0000-0002-3641-6281
Emanuel Fournier-RossDepartment of Medicine, Université de Montréal, Montréal, QC, Canada.
Hubert Tessier-GrenierFaculty of Medicine, Université de Montréal, Montréal, QC, Canada.
Louis-Antoine MullieDepartment of Medicine, Université de Montréal, Montréal, QC, Canada.ORCID http://orcid.org/0000-0001-8668-675X
Michaël ChasséDivision of Critical Care, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
François Martin CarrierDivision of Critical Care, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada. francois.martin.carrier@umontreal.ca.ORCID http://orcid.org/0000-0003-0310-0616
Université de Montréal · CACentre Hospitalier de l’Université de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of obesity on outcomes in acute respiratory distress syndrome (ARDS) is not well understood and remains controversial. Recent studies suggest that obesity might be associated with higher morbidity and mortality in respiratory disease caused by SARS-CoV-2 (COVID-19 disease). Our objective was to evaluate the association between obesity and hospital mortality in critical COVID-19 patients.

methodsWe conducted a retrospective cohort study in a tertiary academic center located in Montréal between March and August 2020. We included all consecutive adult patients admitted to the ICU for COVID-19-confirmed respiratory disease. Our main outcome was hospital mortality. We estimated the association between obesity, using the body mass index as a continuous variable, and hospital survival by fitting a multivariable Cox proportional hazards model.

resultsWe included 94 patients. Median [q1, q3] body mass index (BMI) was 29 [26-32] kg/m

conclusionsObesity was prevalent in hospitalized patients with critical illness secondary to COVID-19 disease and a higher BMI was associated with higher hospital mortality. Further studies are needed to validate this association and to better understand its underlying mechanisms.

Indexed as

Hospital MortalityAdultAgedBody Mass IndexComorbidityCOVID-19Critical IllnessFemaleHumansMaleMiddle AgedObesityQuebecRetrospective StudiesSurvival Analysis

Identifiers

PMID34433907
PMCPMC8385700
OpenAlexW3193496722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.