Observational studyNature communications2021
Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage.
Observational study in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 113 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Point-of-care Low-field Magnetic Resonance Imaging in Acute Stroke (POCS) Study
Validation of Low Field MRI in Patients With Stroke Symptoms Less Than 12 Hours
Who cites it
113 citing papers in PubMed.
- Ultra-Low-Field Portable Magnetic Resonance Imaging Feasibility and Safety in Pediatric and Neonatal Extracorporeal Membrane Oxygenation: A Single-Center Year-Long Experience.Journal of the American Heart Association · 2025Trial
- Feasibility of and experience using a portable MRI scanner in the neonatal intensive care unit.Archives of disease in childhood. Fetal and neonatal edition · 2023Trial
- Assessing the utility of low resolution brain imaging: treatment of infant hydrocephalus.NeuroImage. Clinical · 2021Trial
- Advancing the Volumetric Analysis of Ultra-Low-Field Brain MRI Using Image-to-Image Translation.Magnetic resonance in medicine · 2026Article
- Patient and Family Perspectives on Point-of-Care Low-Field Brain Magnetic Resonance Imaging for Children in the Emergency Department, Intensive Care Unit, and Hospital Setting.Pediatric neurology · 2026Article
- Magnetic resonance imaging.Science advances · 2026Review
- Neuroimaging access in Chad: Infrastructure barriers and opportunities for accessible magnetic resonance imaging.medRxiv : the preprint server for health sciences · 2026Article
- MultidimensionalbioRxiv : the preprint server for biology · 2026Article
- Helium Supply-Chain Vulnerability of MRI Services: A Global Ecological Analysis of Imaging Capacity and Health-System Resilience.NMR in biomedicine · 2026Article
- Concomitant Gradient Effects Across Field Strengths and Gradient Amplitudes: Improved Estimation of Errors and Correction of Concomitant Dephasing and Diffusion Weighting.Magnetic resonance in medicine · 2026Article
- Detection of Hemorrhagic Transformation of Cerebral Infarcts with Ultra-low Field MRI.Clinical neuroradiology · 2026Article
- Review
- Role of Low-Field MRI in Acute Stroke.Stroke · 2026Review
- Noise-Level Adaptive Diffusion Priors for Zero-Shot Low-Field MRI Quality Enhancement.NMR in biomedicine · 2026Article
- Implementation and clinical utility of ultra-low-field portable magnetic resonance imaging for postprocedural neurological evaluation in ambulatory neurosurgery: illustrative cases.Journal of neurosurgery. Case lessons · 2026Article
- miniMORPH: A Morphometry Pipeline for Low-Field MRI in Infants.Human brain mapping · 2026Article
- The potential of low-field MRI for global dementia care.Nature reviews. Neurology · 2026Review
- Clinical implementation of ultra-low-field portable MRI in the neuro-intensive care and stroke unit.Neuroradiology · 2026Article
- State-Referenced Truncated SVD for Dynamic Microwave Monitoring of Intracranial Hemorrhage.Biosensors · 2026Article
- Ultra-low fieldCommunications chemistry · 2026Article
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors.
Funding
Abstract
Radiological examination of the brain is a critical determinant of stroke care pathways. Accessible neuroimaging is essential to detect the presence of intracerebral hemorrhage (ICH). Conventional magnetic resonance imaging (MRI) operates at high magnetic field strength (1.5-3 T), which requires an access-controlled environment, rendering MRI often inaccessible. We demonstrate the use of a low-field MRI (0.064 T) for ICH evaluation. Patients were imaged using conventional neuroimaging (non-contrast computerized tomography (CT) or 1.5/3 T MRI) and portable MRI (pMRI) at Yale New Haven Hospital from July 2018 to November 2020. Two board-certified neuroradiologists evaluated a total of 144 pMRI examinations (56 ICH, 48 acute ischemic stroke, 40 healthy controls) and one ICH imaging core lab researcher reviewed the cases of disagreement. Raters correctly detected ICH in 45 of 56 cases (80.4% sensitivity, 95%CI: [0.68-0.90]). Blood-negative cases were correctly identified in 85 of 88 cases (96.6% specificity, 95%CI: [0.90-0.99]). Manually segmented hematoma volumes and ABC/2 estimated volumes on pMRI correlate with conventional imaging volumes (ICC = 0.955, p = 1.69e-30 and ICC = 0.875, p = 1.66e-8, respectively). Hematoma volumes measured on pMRI correlate with NIH stroke scale (NIHSS) and clinical outcome (mRS) at discharge for manual and ABC/2 volumes. Low-field pMRI may be useful in bringing advanced MRI technology to resource-limited settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.