Evidence map›Paper›PMID 34433806›Full record

ArticleNature communications2021

Cognitive insights from tertiary sulci in prefrontal cortex.

Willa I Voorhies, Jacob A Miller, Jewelia K Yao, Silvia A Bunge, Kevin S Weiner

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
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  4. Sulcal anatomy of ventral temporal cortex and reading development.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Genetic insights on the mechanisms of human cortical folding.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
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  10. Variable Presence of an Evolutionarily New Brain Structure Is Related to Trait Impulsivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  11. Article
  12. Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Article
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  15. Article
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  18. Emotion-related impulsivity is related to orbitofrontal cortical sulcation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Willa I VoorhiesDepartment of Psychology, University of California, Berkeley, CA, USA. wvoorhies@berkeley.edu.ORCID http://orcid.org/0000-0003-3276-7129
Jacob A MillerHelen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-6599-7321
Jewelia K YaoPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Silvia A BungeDepartment of Psychology, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-8431-7627
Kevin S WeinerDepartment of Psychology, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-8734-5049
University of California, Berkeley · USPrinceton University · US

Funding

Neuroscience Training Program at UC BerkeleyT32NS095939 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BATEUP, HELEN S. · 2016 to 2025
$6.3M
The role of prefrontal sulcal morphology and brain network architecture in cognitive developmentR21HD100858 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI BUNGE, SILVIA A., WEINER, KEVIN SEAN · 2020 to 2021
$375k
NICHD NIH HHS R21 HD100858NINDS NIH HHS T32 NS095939
6 · The paper itself

Abstract

The lateral prefrontal cortex (LPFC) is disproportionately expanded in humans compared to non-human primates, although the relationship between LPFC brain structures and uniquely human cognitive skills is largely unknown. Here, we test the relationship between variability in LPFC tertiary sulcal morphology and reasoning scores in a cohort of children and adolescents. Using a data-driven approach in independent discovery and replication samples, we show that the depth of specific LPFC tertiary sulci is associated with individual differences in reasoning scores beyond age. To expedite discoveries in future neuroanatomical-behavioral studies, we share tertiary sulcal definitions with the field. These findings support a classic but largely untested theory linking the protracted development of tertiary sulci to late-developing cognitive processes.

Indexed as

CognitionAdolescentBehaviorBrain MappingChildCohort StudiesFemaleHumansMagnetic Resonance ImagingMalePrefrontal Cortex

Identifiers

PMID34433806
PMCPMC8387420
OpenAlexW3194409671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.