Evidence map›Paper›PMID 34433717›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Durvalumab-associated Late-onset Myocarditis Successfully Treated with Corticosteroid Therapy.

Tomoki Maetani, Toka Hamaguchi, Takafumi Nishimura, Satoshi Marumo, Motonari Fukui

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Myocarditis induced by durvalumab in a patient with hepatocellular carcinoma: A case report.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tomoki MaetaniRespiratory Disease Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.
Toka HamaguchiCardiovascular Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.
Takafumi NishimuraDepartment of Medical Oncology, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.
Satoshi MarumoRespiratory Disease Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.
Motonari FukuiRespiratory Disease Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.
Kitano Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 66-year-old man with locally advanced non-small-cell lung cancer (NSCLC) who developed durvalumab-associated myocarditis. The patient underwent durvalumab administration every two weeks following concurrent chemoradiotherapy, without any adverse events or apparent disease progression. He presented with fatigue and dyspnea on exertion seven months after the first administration. Myocarditis was suspected based on laboratory data, an electrocardiogram, echocardiography, and magnetic resonance imaging findings. The definitive diagnosis was confirmed by a myocardial biopsy. Myocarditis was alleviated by cessation of durvalumab and corticosteroid therapy. This is a noteworthy case to describe late-onset myocarditis following the administration of durvalumab for NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMyocarditisAdrenal Cortex HormonesAgedAntibodies, MonoclonalChemoradiotherapyHumansMaleAdrenal Cortex HormonesAntibodies, MonoclonaldurvalumabdurvalumabirAElung cancermyocarditis

Identifiers

PMID34433717
PMCPMC8907760
OpenAlexW3195541851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.