Evidence map›Paper›PMID 34433713›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports.

Yu Ito, Nobuyasu Awano, Fumiya Uchiyama, Minoru Inomata, Naoyuki Kuse, Mari Tone, Kohei Takada, Kazushi Fujimoto, Yutaka Muto, Shogo Sagisaka and 6 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yu ItoDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Nobuyasu AwanoDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Fumiya UchiyamaDepartment of Interventional Radiology, Japanese Red Cross Medical Center, Japan.
Minoru InomataDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Naoyuki KuseDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Mari ToneDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Kohei TakadaDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Kazushi FujimotoDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Yutaka MutoDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Shogo SagisakaDepartment of Emergency and Critical Care Medicine, Japanese Red Cross Medical Center, Japan.
Kenro MakiDepartment of Emergency and Critical Care Medicine, Japanese Red Cross Medical Center, Japan.
Ryuta YamashitaDepartment of Emergency and Critical Care Medicine, Japanese Red Cross Medical Center, Japan.
Akinori HaradaDepartment of Interventional Radiology, Japanese Red Cross Medical Center, Japan.
Jun-Ichi NishimuraDepartment of Interventional Radiology, Japanese Red Cross Medical Center, Japan.
Munehiro HayashiDepartment of Emergency and Critical Care Medicine, Japanese Red Cross Medical Center, Japan.
Takehiro IzumoDepartment of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In hospitalized coronavirus disease 2019 (COVID-19) patients, anticoagulation therapy is administered to prevent thrombosis. However, anticoagulation sometimes causes bleeding complications. We herein report two Japanese cases of severe COVID-19 in which spontaneous muscle hematomas (SMH) developed under therapeutic anticoagulation with unfractionated heparin. Although the activated partial prothrombin time was within the optimal range, contrast-enhanced computed tomography (CECT) revealed SMH in the bilateral iliopsoas muscles in both cases, which required emergent transcatheter embolization. Close monitoring of the coagulation system and the early diagnosis of bleeding complications through CECT are needed in severe COVID-19 patients treated with anticoagulants.

Indexed as

COVID-19HeparinAnticoagulantsHematomaHumansJapanMusclesSARS-CoV-2AnticoagulantsHeparinCOVID-19spontaneous muscle hematomatherapeutic anticoagulationunfractionated heparinvascular dysfunction

Identifiers

PMID34433713
PMCPMC8627824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.