ArticleProceedings of the National Academy of Sciences of the United States of America2021
SLC-30A9 is required for Zn
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
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Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- The SLC-ome of membrane transport: from molecular discovery to physiology and clinical applications.Physiological reviews · 2026Review
- Iron and Other Metal Ions in Human Health and Disease.MedComm · 2026Review
- Zinc dyshomeostasis, mitochondrial dysfunction, and their pathological cycle in ischemic stroke pathophysiology: Mechanisms and potential therapeutic targets.Redox biology · 2026Review
- Mitochondrial degradation of metallothionein enables local zinc mobilization during zinc limitation.bioRxiv : the preprint server for biology · 2026Article
- Zinc as a master regulator of intracellular organelle homeostasis.Experimental & molecular medicine · 2026Review
- The NAT10/acCell communication and signaling : CCS · 2026Review
- Integrated DIA proteomics and transcriptomics unravel molecular mechanisms of uterine prolificacy in Yunshang Black goats during the estrous cycle.BMC genomics · 2026Article
- Overview of the Zinc Functional Interactome Through Health Hallmarks and Medical Conditions.Nutrients · 2026Review
- PRDM1-driven SLC30A9 overexpression contributes to the malignant phenotype of cervical cancer cells via promoting mitochondrial hyperfunction.Cell death & disease · 2025Article
- Chewing loads alter TMJ metabolism and Zn homeostasis via PIEZO1/ TRPV4.Journal of biological engineering · 2025Article
- Article
- SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: from gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy.Frontiers in immunology · 2025Review
- Engineered bio-functional material-based nerve guide conduits for optic nerve regeneration: a view from the cellular perspective, challenges and the future outlook.Regenerative biomaterials · 2025Review
- SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus.Cellular and molecular life sciences : CMLS · 2024Article
- SLC30A9: an evolutionarily conserved mitochondrial zinc transporter essential for mammalian early embryonic development.Cellular and molecular life sciences : CMLS · 2024Article
- N-acetyltransferase 10 facilitates tumorigenesis of diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling through N4-acetylcytidine modification of SLC30A9.Clinical and translational medicine · 2024Article
- Transcriptomic analysis reveals the crosstalk between type 2 diabetes and chronic pancreatitis.Health science reports · 2024Article
- Biodegradable Zn-5Dy Alloy with Enhanced Osteo/Angio-Genic Activity and Osteointegration Effect via Regulation of SIRT4-Dependent Mitochondrial Function.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Human genetic adaptation related to cellular zinc homeostasis.PLoS genetics · 2023Article
- Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 2 countries.
Huichao DengNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-1758-1820
Xinhua QiaoNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Ting XieNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wenfeng FuNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-2912-6443
Hang LiNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yanmei ZhaoKey Laboratory of RNA Biology, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-3294-6971
Miaomiao GuoNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yaqian FengSchool of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, China.
Ligong ChenSchool of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, China.
Yan ZhaoNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Long MiaoCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.ORCID 0000-0002-0562-6681
Chang ChenNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; changchen@moon.ibp.ac.cn kangshen@stanford.edu xmwang@ibp.ac.cn.
Kang ShenHHMI, Stanford University, Stanford, CA 94305; changchen@moon.ibp.ac.cn kangshen@stanford.edu xmwang@ibp.ac.cn.
Xiangming WangNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; changchen@moon.ibp.ac.cn kangshen@stanford.edu xmwang@ibp.ac.cn.ORCID 0000-0002-5111-0512
Chinese Academy of Sciences · CNTsinghua University · CNStanford University · US
Funding
Howard Hughes Medical Institute
Abstract
The trace element zinc is essential for many aspects of physiology. The mitochondrion is a major Zn
Indexed as
AnimalsAxonsCaenorhabditis elegansCaenorhabditis elegans ProteinsCation Transport ProteinsCell Cycle ProteinsDendritesFemaleGene Knockout TechniquesHeLa CellsHomeostasisHumansMaleMembrane Potential, MitochondrialMitochondriaMutationCaenorhabditis elegans ProteinsCation Transport ProteinsCell Cycle ProteinsSLC30A9 protein, humanTranscription FactorsZincBirk–Landau–Perez cerebrorenal syndromemitochondriaSLC-30A9Zn2+ transporters
Identifiers
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.