Evidence map›Paper›PMID 34433625›Full record

ArticleImmunoHorizons2021

Selectin Dependence of Allergic Skin Inflammation Is Diminished by Maternal Atopy.

Ibrahim M Khan, Benjamin J Ulrich, Andrew S Nelson, Sarita Sehra, Geoffrey S Kansas, Mark H Kaplan

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Current Insights on the Impact of Proteomics in Respiratory Allergies.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ibrahim M KhanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN.ORCID 0000-0002-3004-9361
Benjamin J UlrichDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN.
Andrew S NelsonDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN.
Sarita SehraHerman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN; and.
Geoffrey S KansasDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-0256-3005
Mark H KaplanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN; mkaplan2@iu.edu.ORCID 0000-0002-2923-8245
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · USNorthwestern University · US

Funding

Project-005U54DK106846 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Reuben Kapur, Karen Elizabeth Pollok · 2015 to 2026
$9.7M
BASIC SCIENCE STUDIES ON GENE THERAPY OF BLOOD DISEASEST32HL007910 · NHLBI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Roland W. Herzog, Reuben Kapur · 1999 to 2026
$7.6M
Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Indiana Medical Scientist/Engineer Training ProgramT32GM077229 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN, HERBERT, BRITTNEY-SHEA · 2008 to 2022
$6.0M
Cytokine regulation of skin barrier functionR01AI095282 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI KAPLAN, MARK H · 2012 to 2022
$4.3M
IL-9-secreting tissue-resident memory T cells in allergic airway diseaseF30HL147515 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI ULRICH, BENJAMIN · 2019 to 2019
$30k
NHLBI NIH HHS F30 HL147515NHLBI NIH HHS T32 HL007910NIAID NIH HHS R01 AI095282NIAID NIH HHS T32 AI060519NIDDK NIH HHS U54 DK106846NIGMS NIH HHS T32 GM077229
6 · The paper itself

Abstract

Allergic skin inflammation requires the influx of inflammatory cells into the skin. Extravasation of leukocytes into the skin requires interactions between endothelial selectins and their glycan ligands on the surface of leukocytes. Selectin-ligand formation requires the activity of several glycosyltransferases, including

Indexed as

AnimalsCD4-Positive T-LymphocytesCytokinesDermatitis, AtopicE-SelectinFucosyltransferasesHumansImmunity, Maternally-AcquiredInflammationLeukocytesMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicP-SelectinSkinCytokinesE-SelectinFucosyltransferasesfucosyltransferase VII, mouseP-SelectinSTAT6 Transcription Factor

Identifiers

PMID34433625
PMCPMC8638165
OpenAlexW3195882480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.