Evidence map›Paper›PMID 34433512›Full record

ReviewBiological psychiatry2022

A Framework for Developing Translationally Relevant Animal Models of Stress-Induced Changes in Eating Behavior.

Marie François, Olaya Fernández-Gayol, Lori M Zeltser

Open access · greenAbstract readReview
In one paragraph

Review in Biological psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Identification of a neural basis for anorexia nervosa.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Daily social resources as a buffer against stress eating and its consequences.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. A paraventricular thalamus to insular cortex glutamatergic projection gates "emotional" stress-induced binge eating in females.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marie FrançoisNaomi Berrie Diabetes Center, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, New York.
Olaya Fernández-GayolNaomi Berrie Diabetes Center, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, New York.
Lori M ZeltserNaomi Berrie Diabetes Center, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, New York; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York. Electronic address: lz146@cumc.columbia.edu.
Columbia University Irving Medical Center · US

Funding

Functional mapping of arginine vasopressin receptor 1A circuits that promote anorexic behaviorR01MH113353 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZELTSER, LORI M · 2018 to 2022
$2.3M
NIMH NIH HHS R01 MH113353
6 · The paper itself

Abstract

Stress often affects eating behaviors, leading to increased eating in some individuals and decreased eating in others. Identifying physiological and psychological factors that determine the direction of eating responses to stress has been a major goal of epidemiological and clinical studies. However, challenges of standardizing the stress exposure in humans hinder efforts to uncover the underlying mechanisms. The issue of what determines the direction of stress-induced feeding responses has not been directly addressed in animal models, but assays that combine stress with a feeding-related task are commonly used as readouts of other behaviors, such as anxiety. Sex, estrous cyclicity, circadian cyclicity, caloric restriction, palatable diets, elevated body weight, and properties of the stressors similarly influence feeding behavior in humans and rodent models. Yet, most rodent studies do not use conditions that are most relevant for studying feeding behavior in humans. This review proposes a conceptual framework for incorporating these influences to develop reproducible and translationally relevant assays to study effects of stress on food intake. Such paradigms have the potential to uncover links between emotional eating and obesity as well as to the etiology of eating disorders.

Indexed as

Feeding and Eating DisordersFeeding BehaviorAnimalsAnxietyDietDisease Models, AnimalEatingStress, PsychologicalAnhedoniaAnimal modelsEating disordersEmotional eatingNovelty suppressed feedingStress

Identifiers

PMID34433512
PMCPMC8720907
OpenAlexW3183128879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.