Evidence map›Paper›PMID 34433492›Full record

ArticleMicrobiome2021

Breed differences in the expression levels of gga-miR-222a in laying hens influenced H

Si-Cheng Xing, Chun-Bo Huang, Rui-Ting Wu, Yi-Wen Yang, Jing-Yuan Chen, Jian-Dui Mi, Yin-Bao Wu, Yan Wang, Xin-Di Liao

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Frontiers in nutrition · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 3 countries.

Si-Cheng Xing *College of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Chun-Bo Huang *College of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Rui-Ting WuCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Yi-Wen YangCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Jing-Yuan ChenCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Jian-Dui MiCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Yin-Bao WuCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Yan WangCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China.
Xin-Di LiaoCollege of Animal Science, South China Agricultural University, Guangzhou, 510642, China. xdliao@scau.edu.cn.ORCID 0000-0003-3409-2866
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe microbiota in the cecum of laying hens is crucial for host digestion, metabolism, and odor gas production. The results of recent studies have suggested that host microRNAs (miRNAs) can regulate gene expression of the gut microbiota. In the present study, the expression profiles of host-derived miRNAs in the cecal content of two laying hen breeds; Hy-line Gray and Lohmann Pink, which have dissimilar H

resultsThe differential expression of microbial serine O-acetyltransferase, methionine synthase, aspartate aminotransferase, methionine-gamma-lyase, and adenylylsulfate kinase between the two hen breeds resulted in lower H

conclusionThe findings of the present study reveal both a physiological role by which miRNAs shape the cecal microbiota of laying hens and a strategy to use host miRNAs to manipulate the microbiome and actively express key microbial genes to reduce H

Indexed as

ChickensMicroRNAs5-Methyltetrahydrofolate-Homocysteine S-MethyltransferaseAnimalsBacteriaCecumFemale5-Methyltetrahydrofolate-Homocysteine S-MethyltransferaseMicroRNAsgga-miR-222aHydrogen sulfideLaying hensMetatranscriptomemiRNA

Identifiers

PMID34433492
PMCPMC8390279
OpenAlexW3115227043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.