ArticleCirculation research2021
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
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- Infusible Extracellular Matrix Biomaterial Enhances Cell-Specific Pro-Repair Responses Following Acute Myocardial Infarction.Advanced healthcare materials · 2026Article
- Osteopontin in Atrial Fibrillation and Atrial Remodeling.Journal of the American Heart Association · 2026Review
- Infusible Extracellular Matrix Biomaterial Enhances Cell-Specific Pro-Repair Responses Following Acute Myocardial Infarction.bioRxiv : the preprint server for biology · 2025Article
- PLK2 and the GSK3β-NRF2 Axis: A Promising Therapeutic Target for Sepsis-Induced Cardiac Injury?American journal of hypertension · 2025Article
- Decreased PLK2 promotes atrial fibrillation in diabetic mice through Nrf2/HO-1 pathway.Acta diabetologica · 2025Article
- Epicardial Adipose Tissue-A Novel Therapeutic Target in Obesity Cardiomyopathy.International journal of molecular sciences · 2025Review
- Atrial remodelling and atrial fibrillation self-sustaining: the role of circulating circDGCR8.Cardiovascular research · 2025Article
- Patterning Defects in Mice with Defective Ventricular Wall Maturation and Cardiomyopathy.Journal of cardiovascular development and disease · 2025Article
- Polo-like kinase2 regulates renal tubulointerstitial fibrosis via notch signaling pathway in diabetic kidney disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Radiation-induced morphea of the breast - characterization and treatment of fibroblast dysfunction with repurposed mesalazine.Scientific reports · 2024Article
- Synergistic Effects of Weight Loss and Catheter Ablation: Can microRNAs Serve as Predictive Biomarkers for the Prevention of Atrial Fibrillation Recurrence?International journal of molecular sciences · 2024Review
- Examining the Long-Term Prognostic Significance of Serum sST2: Influence of Myocardial Infarction History and Subgroup Level Standardization.Journal of inflammation research · 2024Article
- Cardiac arrhythmogenesis: roles of ion channels and their functional modification.Frontiers in physiology · 2024Review
- Recruited macrophages elicit atrial fibrillation.Science (New York, N.Y.) · 2023Article
- PI3K(p110α) as a determinant and gene therapy for atrial enlargement in atrial fibrillation.Molecular and cellular biochemistry · 2023Review
- CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2.Circulation research · 2023Article
- Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca2+ mishandling and atrial fibrosis in active immunization rabbit models.Clinical science (London, England : 1979) · 2023Article
- Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.Nature communications · 2022Article
- Fibroblast-Secreted Phosphoprotein 1 Mediates Extracellular Matrix Deposition and Inhibits Smooth Muscle Cell Contractility in Marfan Syndrome Aortic Aneurysm.Journal of cardiovascular translational research · 2022Article
Corrections and comments
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Authors and funding
32 authors at 13 institutions in 7 countries.
Stephan R Künzel *Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Maximilian Hoffmann *Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).ORCID 0000-0003-3427-8409
Silvio WeberInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Karolina KünzelInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Susanne KämmererInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Mario GünschtInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).ORCID 0000-0003-1686-6442
Erik KlapprothInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Johanna S E RauschInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Mirna S SadekInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Tomasz KolanowskiInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).ORCID 0000-0003-3898-8272
Stefanie Meyer-RoxlauInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Christopher PiorkowskiDepartment of Rhythmology (C.P., M.W.), Clinic for Internal Medicine and Cardiology, Heart Center Dresden GmbH, Dresden, Technische Universität Dresden.ORCID 0000-0003-1103-7944
Sems M TugtekinDepartment of Cardiac Surgery (S.M.T.), Clinic for Internal Medicine and Cardiology, Heart Center Dresden GmbH, Dresden, Technische Universität Dresden.
Stefan Rose-JohnUnit for Degradomics of the Protease Web, Institute of Biochemistry, University of Kiel (S.R.-J.).
Xiaoke YinThe James Black Centre, King's College, University of London (X.Y., M.M.).ORCID 0000-0002-5172-0935
Manuel MayrThe James Black Centre, King's College, University of London (X.Y., M.M.).ORCID 0000-0002-0597-829X
Jan Dominik KuhlmannDepartment of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden (J.D.K., P.W.).
Pauline WimbergerDepartment of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden (J.D.K., P.W.).ORCID 0000-0002-7380-577X
Konrad GrützmannInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Natalie HerzogBrandenburg University of Technology, Senftenberg (N.H., J.-H.K.).
Jan-Heiner KüpperBrandenburg University of Technology, Senftenberg (N.H., J.-H.K.).
Molly O'ReillyInstitute of Cardiovascular Sciences, University of Birmingham (M.O., S.N.K., L.C.S.).ORCID 0000-0003-1936-5838
S Nashitha KabirInstitute of Cardiovascular Sciences, University of Birmingham (M.O., S.N.K., L.C.S.).
Laura C SommerfeldInstitute of Cardiovascular Sciences, University of Birmingham (M.O., S.N.K., L.C.S.).ORCID 0000-0001-9837-8770
Kaomei GuanORCID 0000-0002-0753-3083
Ben WielockxInstitute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden (B.W.).ORCID 0000-0002-4923-2596
Larissa FabritzDepartment of Cardiology, University Hospitals Birmingham (L.F.).ORCID 0000-0002-9241-1733
Stanley NattelDepartment of Medicine, Montreal Heart Institute and Université de Montréal, Quebec, Canada (S.N., D.D.).ORCID 0000-0002-5565-3311
Ursula RavensInstitut für Experimentelle Kardiovaskuläre Medizin, Universitäts Herzzentrum, Freiburg Bad Krotzingen, Freiburg im Breisgau (U.R.).
Dobromir DobrevDepartment of Medicine, Montreal Heart Institute and Université de Montréal, Quebec, Canada (S.N., D.D.).ORCID 0000-0002-4612-117X
Michael Wagner *Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).ORCID 0000-0002-6300-5752
Ali El-Armouche *Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).ORCID 0000-0003-2514-9429
Norwegian Womens Public Health Association · NOTechnische Universität Dresden · DEBrandenburg University of Technology Cottbus-Senftenberg · DEGerman Cancer Research Center · DEKing's College London · GBBaylor College of Medicine · USCardiovascular Institute of the South · USKiel Institute for the World Economy · DEMontreal Heart Institute · CANational Center for Tumor Diseases · DEUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity of Alabama at Birmingham Hospital · USUniversity of Birmingham · GB
Funding
British Heart Foundation AA/18/2/34218British Heart Foundation CH/16/3/32406
Abstract
[Figure: see text].
Indexed as
AgedAnimalsAtrial FibrillationCells, CulturedFemaleFibrosisHumansMaleMesalamineMiceMice, Inbred C57BLMiddle AgedMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3MyocardiumMyofibroblastsMesalamineMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3OsteopontinPLK2 protein, humanProtein Kinase InhibitorsProtein Serine-Threonine Kinasesatrial fibrillationfibroblastsfibrosismesalamineosteopontin
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