Trial reportCell reports2021
Functional harmonics reveal multi-dimensional basis functions underlying cortical organization.
Trial report in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- N,N-dimethyltryptamine effects on connectome harmonics, subjective experience and comparative psychedelic experiences.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness.British journal of anaesthesia · 2025Article
- Investigating the complex cortical dynamics of an advanced concentrative absorption meditation called jhanas (ACAM-J): a geometric eigenmode analysis.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Mapping the white-matter functional connectome: a personal perspective.Psychoradiology · 2025Review
- Structure-function coupling and decoupling during movie watching and resting state: Novel insights bridging EEG and structural imaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Modelling low-dimensional interacting brain networks reveals organising principle in human cognition.Network neuroscience (Cambridge, Mass.) · 2025Article
- Systematic evaluation of fMRI data-processing pipelines for consistent functional connectomics.Nature communications · 2024Article
- Time-resolved coupling between connectome harmonics and subjective experience under the psychedelic DMT.bioRxiv : the preprint server for biology · 2024Article
- The flattening of spacetime hierarchy of theNational science review · 2024Article
- Decomposing cortical activity through neuronal tracing connectome-eigenmodes in marmosets.Nature communications · 2024Article
- Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain.Nature communications · 2024Article
- Local gradient analysis of human brain function using the Vogt-Bailey Index.Brain structure & function · 2024Article
- Omnipresence of the sensorimotor-association axis topography in the human connectome.NeuroImage · 2023Article
- Complex spatiotemporal oscillations emerge from transverse instabilities in large-scale brain networks.PLoS computational biology · 2023Article
- Distributed harmonic patterns of structure-function dependence orchestrate human consciousness.Communications biology · 2023Article
- Toward naturalistic neuroscience: Mechanisms underlying the flattening of brain hierarchy in movie-watching compared to rest and task.Science advances · 2023Article
- A dynamic gradient architecture generates brain activity states.NeuroImage · 2022Article
- Understanding brain states across spacetime informed by whole-brain modelling.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Review
- Advancing brain network models to reconcile functional neuroimaging and clinical research.NeuroImage. Clinical · 2022Review
- Revisiting the global workspace orchestrating the hierarchical organization of the human brain.Nature human behaviour · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human brain consists of specialized areas that flexibly interact to form a multitude of functional networks. Complementary to this notion of modular organization, brain function has been shown to vary along a smooth continuum across the whole cortex. We demonstrate a mathematical framework that accounts for both of these perspectives: harmonic modes. We calculate the harmonic modes of the brain's functional connectivity graph, called "functional harmonics," revealing a multi-dimensional, frequency-ordered set of basis functions. Functional harmonics link characteristics of cortical organization across several spatial scales, capturing aspects of intra-areal organizational features (retinotopy, somatotopy), delineating brain areas, and explaining macroscopic functional networks as well as global cortical gradients. Furthermore, we show how the activity patterns elicited by seven different tasks are reconstructed from a very small subset of functional harmonics. Our results suggest that the principle of harmonicity, ubiquitous in nature, also underlies functional cortical organization in the human brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.