ArticleCell reports2021
Mesoscopic physiological interactions in the human brain reveal small-world properties.
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Brain network analysis using morphological intrinsic divergence: differences in small-world properties of morphological similarity networks among healthy young adults with different chronotypes.Brain imaging and behavior · 2026Article
- Investigating changes of functional brain networks in painful temporomandibular disorders: a resting-state fMRI study.Journal of oral & facial pain and headache · 2026Article
- Article
- Synchronization in fractional-order neural networks by the energy balance strategy.Cognitive neurodynamics · 2024Article
- Functional geometry of auditory cortical resting state networks derived from intracranial electrophysiology.PLoS biology · 2023Article
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5 authors.
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Abstract
Cognition depends on rapid and robust communication between neural circuits spanning different brain areas. We investigated the mesoscopic network of cortico-cortical interactions in the human brain in an extensive dataset consisting of 6,024 h of intracranial field potential recordings from 4,142 electrodes in 48 subjects. We evaluated communication between brain areas at the network level across different frequency bands. The interaction networks were validated against known anatomical measurements and neurophysiological interactions in humans and monkeys. The resulting human brain interactome is characterized by a broad and spatially specific, dynamic, and extensive network. The physiological interactome reveals small-world properties, which we conjecture might facilitate efficient and reliable information transmission. The interaction dynamics correlate with the brain sleep/awake state. These results constitute initial steps toward understanding how the interactome orchestrates cortical communication and provide a reference for future efforts assessing how dysfunctional interactions may lead to mental disorders.
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Registered trials
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