Evidence map›Paper›PMID 34433027›Full record

ArticleCell reports2021

Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors.

Justin N Siemian, Miguel A Arenivar, Sarah Sarsfield, Cara B Borja, Charity N Russell, Yeka Aponte

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 53 citations in OpenAlex.

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  13. Sequential Activation of Lateral Hypothalamic Neuronal Populations during Feeding and Their Assembly by Gamma Oscillations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  14. The cognitive (lateral) hypothalamus.Trends in cognitive sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Justin N SiemianNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA.
Miguel A ArenivarNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA.
Sarah SarsfieldNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA.
Cara B BorjaNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA.
Charity N RussellNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA.
Yeka AponteNeuronal Circuits and Behavior Unit, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-6823, USA; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: yeka.aponte@nih.gov.
National Institute on Drug Abuse · USNational Institutes of Health · US

Funding

Hypothalamic neuronal circuits controlling survival behaviorsZIADA000595 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI APONTE, YEKA · 2013 to 2025
$21.3M
Intramural NIH HHS ZIA DA000595
6 · The paper itself

Abstract

Assigning behavioral roles to genetically defined neurons within the lateral hypothalamus (LH) is an ongoing challenge. We demonstrate that a subpopulation of LH GABAergic neurons expressing leptin receptors (LH

Indexed as

AnimalsAppetitive BehaviorBehavior, AnimalHypothalamic Area, LateralLearningMice, TransgenicOptogeneticsRewardVentral Tegmental Areaappetitive behaviorschemogeneticsconsummatory behaviorsfunctional imaginglateral hypothalamusleptin receptorneuronal circuitsoptogeneticsventral tegmental area

Identifiers

PMID34433027
PMCPMC8423025
OpenAlexW3193644438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.