Evidence map›Paper›PMID 34432866›Full record

ArticleBlood2021

Primary cytotoxic T-cell lymphomas harbor recurrent targetable alterations in the JAK-STAT pathway.

Katie Lee, Mark G Evans, Lei Yang, Spencer Ng, Caroline Snowden, Michael Khodadoust, Ryanne A Brown, Nicholas A Trum, Christiane Querfeld, Linda T Doan and 13 more

Abstract readLetter
In one paragraph

Article in Blood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Through thick and thin: confronting the aggressive cutaneous T-cell lymphomas.Hematology. American Society of Hematology. Education Program · 2024
    Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Katie LeeDepartment of Dermatology and.ORCID 0000-0002-9919-4962
Mark G EvansDepartment of Pathology, Brigham and Women's Hospital and.ORCID 0000-0001-9358-9843
Lei YangDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
Spencer NgDepartment of Dermatology and.ORCID 0000-0002-1251-4514
Caroline SnowdenDepartment of Dermatology and.
Michael KhodadoustDivision of Oncology, Department of Medicine.ORCID 0000-0001-9061-7351
Ryanne A BrownDepartment of Dermatology and.ORCID 0000-0001-9099-7227
Nicholas A TrumDepartment of Dermatology, City of Hope National Medical Center, Duarte, CA.ORCID 0000-0002-3256-4340
Christiane QuerfeldDepartment of Dermatology, City of Hope National Medical Center, Duarte, CA.ORCID 0000-0001-9698-5809
Linda T DoanDepartment of Dermatology, University of California, Irvine, Irvine, CA.
Jinming SongDepartment of Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Hailing ZhangDepartment of Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Alejandro A GruDepartment of Pathology, University of Virginia, Charlottesville, VA.
Gary S WoodDepartment of Dermatology, University of Wisconsin, Madison, WI.
David A WadaDepartment of Dermatology and.
Vignesh ShanmugamDepartment of Pathology, Brigham and Women's Hospital and.
Paul L HaunPenn Cutaneous Lymphoma Program, Department of Dermatology, Perelman Center for Advanced Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Jon C AsterDepartment of Pathology, Brigham and Women's Hospital and.
Lyn M DuncanDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Joan GuitartDepartment of Dermatology and.
David M WeinstockDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.ORCID 0000-0002-8724-3907
Valentina NardiDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Jaehyuk ChoiDepartment of Dermatology and.ORCID 0000-0003-2379-2226

Funding

Targeting oncogenic TCR signaling in PTCLP01CA233412 · NCI · DANA-FARBER CANCER INST · PI ASTER, JON C. · 2019 to 2023
$8.7M
Northwestern University Skin Disease Research Center Resource-based CenterP30AR075049 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI I. Caroline Le Poole · 2019 to 2026
$6.6M
Targeting High-Risk Lymphoid NeoplasmsR35CA231958 · NCI · DANA-FARBER CANCER INST · PI WEINSTOCK, DAVID MARC · 2019 to 2021
$2.9M
Skin Diseases Research Center at the University of WisconsinP30AR066524 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI LONGLEY, B JACK · 2014 to 2018
$2.6M
Identifying Mechanisms Governing T Cell DiversityDP2AI136599 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHOI, JAEHYUK · 2017 to 2017
$2.4M
NCI NIH HHS P01 CA233412NCI NIH HHS R35 CA231958NIAID NIH HHS DP2 AI136599NIAMS NIH HHS P30 AR066524NIAMS NIH HHS P30 AR075049
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAntineoplastic AgentsHumansJanus KinasesLymphoma, T-CellMolecular Targeted TherapyMutationSTAT Transcription FactorsAntineoplastic AgentsJanus KinasesSTAT Transcription Factors

Identifiers

PMID34432866
PMCPMC8662071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.