Evidence map›Paper›PMID 34432835›Full record

ArticlePloS one2021

Can follow up lung ultrasound in Coronavirus Disease-19 patients indicate clinical outcome?

Tatjana Hoffmann, Peter Bulla, Lisa Jödicke, Constantin Klein, Sarah M Bott, Ronald Keller, Nisar Malek, Eckhart Fröhlich, Siri Göpel, Gunnar Blumenstock and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
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  5. Article
  6. What Is COVID 19 Teaching Us about Pulmonary Ultrasound?Diagnostics (Basel, Switzerland) · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tatjana HoffmannDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-1014-4652
Peter BullaDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-0456-3869
Lisa JödickeDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Constantin KleinDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Sarah M BottDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Ronald KellerDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Nisar MalekDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Eckhart FröhlichDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Siri GöpelDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
Gunnar BlumenstockDepartment of Clinical Epidemiology, Eberhard-Karls-University, Tübingen, Germany.
Stefano FuscoDepartment of Internal Medicine I, Section of Gastroenterology, Gastrointestinal Oncology, Hepatology, Infectiology and Geriatry, University Hospital Tübingen, Tübingen, Germany.
University of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate whether there is a change in findings of coronavirus disease 2019 patients in follow up lung ultrasound and to determine whether these findings can predict the development of severe disease. MATERIALS AND

methodsIn this prospective monocentric study COVID-19 patients had standardized lung ultrasound (12 area evaluation) at day 1, 3 and 5. The primary end point was detection of pathologies and their change over time. The secondary end point was relationship between change in sonographic results and clinical outcome. Clinical outcome was assessed on development of severe disease defined as need for intensive care unit.

resultsData of 30 patients were analyzed, 26 patients with follow-up lung ultrasound. All of them showed lung pathologies with dynamic patterns. 26,7% developed severe disease tending to have an ubiquitous lung involvement in lung ultrasound. In patients with need for intensive care unit a previously developed increase in B-lines, subpleural consolidations and pleural line irregularities was more common. A statistically significant association between change in B-lines as well as change in pleural line irregularities and development of severe disease was observed (p<0,01).

conclusionThe present study demonstrates that follow up lung ultrasound can be a powerful tool to track the evolution of disease and suggests that lung ultrasound is able to indicate an impending development of severe disease in COVID-19 patients.

Indexed as

AgedAged, 80 and overCOVID-19FemaleFollow-Up StudiesHumansIntensive Care UnitsLungMaleMiddle AgedPleural EffusionProspective StudiesSARS-CoV-2Ultrasonography

Identifiers

PMID34432835
PMCPMC8386874
OpenAlexW3193698583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.