Evidence map›Paper›PMID 34432628›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Impact of nasal dilator strips on measures of sleep-disordered breathing in pregnancy.

Mariko Maxwell, Laura Sanapo, Kristina Monteiro, Maggie Bublitz, Ashanti Avalos, Naya Habr, Ghada Bourjeily

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariko MaxwellWarren Alpert School of Medicine at Brown University, Providence, Rhode Island.
Laura SanapoWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island.
Kristina MonteiroWarren Alpert School of Medicine at Brown University, Providence, Rhode Island.
Maggie BublitzWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island.
Ashanti AvalosWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island.
Naya HabrWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island.
Ghada BourjeilyWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island.
Brown University · USMiriam Hospital · US

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV, HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
Predictors of de novo development of obstructive sleep apnea in pregnancyR01HL130702 · NHLBI · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2016 to 2020
$2.6M
Short-Term Training Program to Increase Diversity in Health-Related ResearchR25HL088992 · NHLBI · BROWN UNIVERSITY · PI ABID, RUHUL, DIAZ, JOSEPH A · 2007 to 2024
$1.9M
Warren Alpert Medical School Basic Translational ResearchT35HL094308 · NHLBI · BROWN UNIVERSITY · PI Thomas Benedict Bartnikas, Brittany Star Hampton · 2009 to 2026
$808k
NHLBI NIH HHS R01 HL130702NHLBI NIH HHS R25 HL088992NHLBI NIH HHS T35 HL094308NIGMS NIH HHS P20 GM103652
6 · The paper itself

Abstract

STUDY

objectivesWomen with sleep-disordered breathing (SDB) in pregnancy are at a greater risk of developing serious adverse perinatal outcomes. However, the pathogenesis of SDB in pregnancy is poorly understood. As nasal congestion is common in pregnancy, nasal obstruction may contribute to SDB in this population. This study aims to assess the impact of nasal dilator strips (NDS) on measures of SDB and their potential for use as a placebo condition.

methodsPregnant women ≥ 18 years old, body mass index ≥ 27 kg/m

results54 women, 59% White, 60% in the third trimester were enrolled. Median time between the 2 studies was 1 day (interquartile range [IQR] 4). There was no significant change between the night without NDS use and the night with NDS use in respiratory event index (5.30 [IQR 6.20] vs 4.80 [IQR 6.78],

conclusionsDespite the high prevalence of pregnancy-associated rhinitis, NDS do not have a significant impact on measures of SDB. Results from this study support the use of NDS as an appropriate placebo in prenatal clinical trials. CITATION: Maxwell M, Sanapo L, Monteiro K, et al. Impact of nasal dilator strips on measures of sleep-disordered breathing in pregnancy.

Indexed as

Sleep Apnea SyndromesAdolescentBody Mass IndexFemaleHumansNasal CavityPolysomnographyPregnancySnoringnasal dilator stripsobstructive sleep apneaplacebopregnancypulse transit timerespiratory event indexsleepsleep-disordered breathing

Identifiers

PMID34432628
PMCPMC8804998
OpenAlexW3193954454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.