Evidence map›Paper›PMID 34432535›Full record

ArticleOmics : a journal of integrative biology2021

How to Achieve Therapeutic Response in Erlotinib-Resistant Head and Neck Squamous Cell Carcinoma? New Insights from Stable Isotope Labeling with Amino Acids in Cell Culture-Based Quantitative Tyrosine Phosphoproteomics.

Ankit P Jain, Aneesha Radhakrishnan, Sneha Pinto, Krishna Patel, Manish Kumar, Vishalakshi Nanjappa, Remya Raja, Thottethodi Subrahmanya Keshava Prasad, Premendu P Mathur, David Sidransky and 2 more

Open access · greenAbstract read
In one paragraph

Article in Omics : a journal of integrative biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Ankit P JainInstitute of Bioinformatics, International Tech Park, Bangalore, India.ORCID 0000-0002-5733-9705
Aneesha RadhakrishnanInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Sneha PintoInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Krishna PatelInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Manish KumarInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Vishalakshi NanjappaInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Remya RajaInstitute of Bioinformatics, International Tech Park, Bangalore, India.
Thottethodi Subrahmanya Keshava PrasadInstitute of Bioinformatics, International Tech Park, Bangalore, India.ORCID 0000-0002-6206-2384
Premendu P MathurSchool of Biotechnology, Kalinga Institute of Industrial Technology, Bhubaneswar, India.
David SidranskyDepartment of Otolaryngology-Head and Neck Surgery; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Aditi ChatterjeeInstitute of Bioinformatics, International Tech Park, Bangalore, India.ORCID 0000-0001-8474-5824
Harsha GowdaInstitute of Bioinformatics, International Tech Park, Bangalore, India.ORCID 0000-0002-4118-6855
Institute of Bioinformatics · INYenepoya University · INManipal Academy of Higher Education · INJohns Hopkins University · USPondicherry University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to cancer chemotherapy is a major global health burden. Epidermal growth factor receptor (

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsAmino AcidsCell Culture TechniquesCell Line, TumorDrug Resistance, NeoplasmErlotinib HydrochlorideHumansIsotope LabelingProtein Kinase InhibitorsSquamous Cell Carcinoma of Head and NeckTyrosineAmino AcidsErlotinib HydrochlorideProtein Kinase InhibitorsTyrosinecancer researcherlotinib resistancefocal adhesion kinasehead and neck cancerquantitative tyrosine phosphoproteomicstyrosine kinase inhibitors

Identifiers

PMID34432535
PMCPMC8591087
OpenAlexW3194756572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.