Evidence map›Paper›PMID 34432496›Full record

ArticleMolecular biology of the cell2021

A dual role for DNA binding by Runt in activation and repression of

Lisa Prazak, Yasuno Iwasaki, Ah-Ram Kim, Konstantin Kozlov, Kevin King, J Peter Gergen

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lisa PrazakDepartment of Biology, Farmingdale State College, Farmingdale, NY 11735-1021.
Yasuno IwasakiDepartment of Biochemistry and Cell Biology and Center for Developmental Genetics.
Ah-Ram KimGraduate Program in Biochemistry and Structural Biology, and.
Konstantin KozlovDepartment of Applied Mathematics, St. Petersburg State Polytechnical University, St. Petersburg, Russia 195251.
Kevin KingDepartment of Biochemistry and Cell Biology and Center for Developmental Genetics.
J Peter GergenDepartment of Biochemistry and Cell Biology and Center for Developmental Genetics.
Stony Brook University · USFarmingdale State College · USPeter the Great St. Petersburg Polytechnic University · RU

Funding

Runt-dependent regulation of enhancer-promoter interactionsR01GM094401 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GERGEN, JOHN PETER · 2011 to 2014
$1.1M
NIGMS NIH HHS R01 GM094401
6 · The paper itself

Abstract

This work investigates the role of DNA binding by Runt in regulating the

Indexed as

AnimalsBody PatterningDNADNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianGene ExpressionGene Expression Regulation, DevelopmentalGenes, InsectHomeodomain ProteinsNuclear ProteinsRegulatory Sequences, Nucleic AcidTranscription FactorsDNADNA-Binding ProteinsDrosophila ProteinsHomeodomain ProteinsNuclear Proteinsrun protein, Drosophilaslp1 protein, DrosophilaTranscription Factors

Identifiers

PMID34432496
PMCPMC8693977
OpenAlexW3194643752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.