Evidence map›Paper›PMID 34432363›Full record

ArticleHIV medicine2021

Chems4EU: chemsex use and its impacts across four European countries in HIV-positive men who have sex with men attending HIV services.

Gary G Whitlock, Konstantinos Protopapas, Jose I Bernardino, Arkaitz Imaz, Adrian Curran, Christof Stingone, Sivapatham Shivasankar, Sarah Edwards, Sophie Herbert, Konstantinos Thomas and 9 more

Open access · hybridAbstract read
In one paragraph

Article in HIV medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
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  11. An online study to understand chemsex in India.Indian journal of psychiatry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 5 countries.

Gary G WhitlockChelsea & Westminster NHS Foundation Trust, London, UK.ORCID 0000-0003-3070-1281
Konstantinos Protopapas4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Jose I BernardinoHIV Unit, Internal Medicine Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.
Arkaitz ImazHIV and STI Unit, Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0001-8411-1952
Adrian CurranInfectious Diseases Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona, Spain.
Christof StingoneDepartment of Experimental Medicine, Tor Vergata University, Rome, Italy.
Sivapatham ShivasankarKent Community NHS Foundation Trust, Kent, UK.
Sarah EdwardsStevenage & Watford clinics, Chelsea & Westminster NHS Foundation Trust, Hertfordshire, UK.
Sophie HerbertNorthamptonshire Healthcare NHS Foundation Trust, Kettering, UK.
Konstantinos Thomas4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Rafael MicanHIV Unit, Internal Medicine Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.
Paula PrietoHIV and STI Unit, Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
Jorge Nestor GarciaInfectious Diseases Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona, Spain.
Massimo AndreoniDepartment of Experimental Medicine, Tor Vergata University, Rome, Italy.
Samantha HillStevenage & Watford clinics, Chelsea & Westminster NHS Foundation Trust, Hertfordshire, UK.
Hajra OkhaiInstitute for Global Health, University College London, London, UK.ORCID 0000-0002-0549-4914
David StuartChelsea & Westminster NHS Foundation Trust, London, UK.ORCID 0000-0003-4056-6730
Adam BourneAustralian Research Centre in Sex, Health & Society, La Trobe University, Melbourne, Vic., Australia.
Katie ConwayKent Community NHS Foundation Trust, Kent, UK.
Bellvitge University Hospital · ESChelsea and Westminster Hospital NHS Foundation Trust · GBHospital Universitario La Paz · ESKent Community Health NHS Foundation Trust · GBNational and Kapodistrian University of Athens · GRUniversity of Rome Tor Vergata · ITVall d'Hebron Institut de Recerca · ESLa Trobe University · AUNorthamptonshire Healthcare NHS Foundation Trust · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChemsex in a European context is the use of any of the following drugs to facilitate sex: crystal methamphetamine, mephedrone and gamma-hydroxybutyrate (GHB)/gamma-butyrolactone (GBL) and, to a lesser extent, cocaine and ketamine. This study describes the prevalence of self-reported recreational drug use and chemsex in HIV-positive men who have sex with men (MSM) accessing HIV services in four countries. It also examines the problematic impacts and harms of chemsex and access to chemsex-related services.

methodsThis is a cross-sectional multi-centre questionnaire study of HIV-positive MSM accessing nine HIV services in the UK, Spain, Greece and Italy.

resultsIn all, 1589 HIV-positive MSM attending HIV services in four countries completed the questionnaire. The median age of participants was 38 years (interquartile range: 32-46 years) and 1525 (96.0%) were taking antiretroviral therapy (ART). In the previous 12 months, 709 (44.6%) had used recreational drugs, 382 (24.0%) reported chemsex and 104 (6.5%) reported injection of chemsex-associated drugs ('slamsex'). Of the 382 engaging in chemsex, 155 (40.6%) reported unwanted side effects as a result of chemsex and 81 (21.2%) as a result of withdrawal from chemsex. The reported negative impacts from chemsex were on work (25.1%, 96), friends/family (24.3%, 93) and relationships (28.3%, 108). Fifty-seven (14.9%) accessed chemsex-related services in the past year, 38 of whom (67%) felt the service met their needs. DISCUSSION: A quarter of participants self-reported chemsex in the past 12 months. There were high rates of harms from chemsex across all countries, including negative impacts on work, friends/family and relationships. Although a minority of those engaging in chemsex accessed support, most found this useful.

Indexed as

HIV InfectionsIllicit DrugsSexual and Gender MinoritiesSubstance-Related DisordersAdultCross-Sectional StudiesHomosexuality, MaleHumansMaleMiddle AgedSexual BehaviorIllicit DrugschemsexHIVMSMrecreational drug

Identifiers

PMID34432363
PMCPMC9290820
OpenAlexW3195020594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.