SynthesisInternational journal of colorectal disease2021
Ovarian metastases from colorectal cancer in young women: a systematic review of the literature.
Synthesis in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Risk of Ovarian Metastasis in Colorectal Cancer-Related Carcinomatosis.Annals of surgical oncology · 2026Article
- Histopathological assessment to detect colorectal ovarian micrometastasis following prophylactic salpingo-oophorectomy in postmenopausal patients.International journal of colorectal disease · 2026Article
- Characteristics and outcomes of patients with pregnancy-associated colorectal cancer.The oncologist · 2025Article
- The difficult diagnosis of a patient presenting with a Krukenberg tumor and Lynch syndrome: a case report.Journal of medical case reports · 2025Article
- Perioperative Outcomes of Postmenopausal Women with Colorectal Cancer Undergoing Prophylactic Salpingo-oophorectomy.South Asian journal of cancer · 2025Article
- Gynecologic Organ Preservation or Resection During CRS/HIPEC for GI Cancers.Annals of surgical oncology · 2025Article
- Management of the Uninvolved Uterus and Adnexa During Routine Pelvic Peritonectomy in Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Varies by Histology and Menopausal Status: An International Survey of Peritoneal Surface Malignancy Surgeons.Annals of surgical oncology · 2025Article
- The heterogeneity of genomic alterations, metastatic patterns and immune microenvironment in metastatic ovarian cancer originating from colorectal cancer.Frontiers in immunology · 2025Article
- Biomarker concordance between primary colorectal cancer and ovarian metastases: a Dutch cohort study.Journal of cancer research and clinical oncology · 2023Article
- Role Of Ovarian Metastases In Colorectal Cancer (ROMIC): a Dutch study protocol to evaluate the effect of prophylactic salpingo-oophorectomy in postmenopausal women.BMC women's health · 2022Article
- Ovarian metastases in young women with colorectal cancer: a retrospective multicenter cohort study.International journal of colorectal disease · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIn female colorectal cancer patients, a mean proportion of synchronous and/or metachronous ovarian metastases of 3.4% was described. Previous literature showed that young or premenopausal women (≤ 55 years of age) may be more frequently affected. Once ovarian metastases are diagnosed, the prognosis of the patient is generally dismal, with 5-year survival varying from 12 to 27%. The present study is aimed at determining the proportion of young or premenopausal women diagnosed with colorectal cancer who presented with or developed ovarian metastases by reviewing the current literature on this topic.
methodsThis review was performed by querying MEDLINE and EMBASE databases using a combination of terms: "colorectal neoplasms, colorectal cancer, ovarian neoplasms, Krukenberg tumor, young adult, young age, premenopause." Studies that indicated ovarian metastases, either synchronous or metachronous (or a combination of the two), in young women were retrieved and analyzed.
resultsThe review identified 14 studies encompassing 3379 young or premenopausal female colorectal cancer patients. In this selected group of patients, a mean proportion of ovarian metastases of 4.6% [95% CI: 4.0;5.4] was found.
conclusionsThis review showed that approximately one in twenty young female colorectal cancer patients will present with or develop ovarian metastases. Since outcome of this specific oncological pathology is often dismal, this finding is clinically relevant. It demonstrates the need to develop strategies to lower the incidence of ovarian metastases with adequate treatment and counseling of these patients.
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