Evidence map›Paper›PMID 34432071›Full record

SynthesisSocial psychiatry and psychiatric epidemiology2021

A systematic review of longitudinal studies of suicidal thoughts and behaviors in first-episode psychosis: course and associated factors.

Roxanne Sicotte, Srividya N Iyer, Barnabé Kiepura, Amal Abdel-Baki

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Social psychiatry and psychiatric epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Roxanne SicotteResearch Center Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.ORCID http://orcid.org/0000-0002-3392-423X
Srividya N Iyer *Department of Psychiatry, McGill University, Montréal, Québec, Canada.ORCID http://orcid.org/0000-0001-5367-9086
Barnabé KiepuraResearch Center Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.
Amal Abdel-Baki *Research Center Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada. amal.abdel-baki@umontreal.ca.ORCID http://orcid.org/0000-0003-3333-9652
Centre for Addiction and Mental Health · CACentre Hospitalier de l’Université de Montréal · CADouglas Mental Health University Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesTo better assess and reduce suicidal risk in first-episode psychosis (FEP), we aimed to investigate the evolution of suicidal thoughts and behaviors (STBs) and associated factors in FEP.

methodThis systematic review (PROSPERO-CRD42020168050) meets PRISMA guidelines. PubMed, Medline, PsycINFO, Embase, EBM Reviews and references lists of relevant articles were searched (February 2020) to identify longitudinal studies, published in English or in French, that assessed the prevalence of STBs at entry to services and over follow-up, and examined factors associated with STBs among all persons with affective and non-affective FEP from a defined catchment area. Screening, data extraction and quality assessment using the adapted Newcastle Ottawa Scale were done independently by two reviewers. Results on prevalence and associated factors are presented by type of STB.

resultsOf 3,177 references, 17 studies of 11 non-overlapping samples (n = 14,907) with varying lengths of follow-up (1-41.7 years) were included. The prevalence of STBs decreased over follow-up. Up to 21.6% made at least one suicide attempt, 27% had suicidal ideation, and 1-4.3% died by suicide during follow-up. Of 53 factors assessed across studies, only male sex, depressive symptoms, and STBs occurring early during follow-up were associated with subsequent STBs. Early intervention for psychosis decreased STBs in the first three years. Other factors were assessed in a single study, yielded conflicting results, or were not associated with STBs.

conclusionsThe high prevalence of STBs following onset of psychosis highlights the need for early detection and intervention and ongoing assessment of suicidal risk throughout follow-up, with attention to identified risk factors. The heterogeneity of the studies precluded a meta-analysis and several factors were each assessed by a single study. Additional well-designed longitudinal studies of STBs and associated factors are warranted.

Indexed as

Psychotic DisordersSuicidal IdeationHumansLongitudinal StudiesMaleRisk FactorsSuicide, AttemptedFirst-episode psychosisSuicidal thoughts and behaviorsSuicideSystematic review

Identifiers

PMID34432071
OpenAlexW3195979038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.