Evidence map›Paper›PMID 34431955›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2021

Analysis of annexin-A1 in the macrophages and apoptotic cells of patients with cutaneous leishmaniasis.

Mariana Nascimento Pona, Jordhana Mendonça Dietrich, Joselina Maria da Silva, Helen Aguiar Lemes da Silva, Marcia Hueb, Amilcar Sabino Damazo

Open access · diamondAbstract read
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mariana Nascimento PonaUniversidade Federal de Mato Grosso, Faculdade de Medicina, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0002-4278-5702
Jordhana Mendonça DietrichUniversidade Federal de Mato Grosso, Programa de Pós-Graduação em Ciências da Saúde, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0003-3545-3360
Joselina Maria da SilvaUniversidade Federal de Mato Grosso, Programa de Pós-Graduação em Ciências da Saúde, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0002-6100-2873
Helen Aguiar Lemes da SilvaUniversidade Federal de Mato Grosso, Programa de Pós-Graduação em Ciências da Saúde, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0002-2070-4115
Marcia HuebUniversidade Federal de Mato Grosso, Faculdade de Medicina, Departamento de Clínica Médica, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0003-1990-458X
Amilcar Sabino DamazoUniversidade Federal de Mato Grosso, Programa de Pós-Graduação em Ciências da Saúde, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0003-2323-008X
Universidade Federal de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to determine the number of macrophages and apoptotic cells and perform annexin-A1 detection in patients with leishmaniasis.

methodsPatients with Leishmania infection were admitted to Júlio Müller University Hospital.

resultsThe number of apoptotic cells was higher in the exudative granulomatous reaction. The exudative cellular reaction displayed higher levels of annexin-A1 detection in macrophages and apoptotic cells. The correlation between annexin-A1 detection in apoptotic cells and macrophages was observed in exudative necrotic reaction and exudative necrotic-granulomatous reaction.

conclusionsOur data demonstrate the relevance of annexin-A1 in the regulation of apoptosis and phagocytosis in leishmaniasis.

Indexed as

Annexin A1Leishmaniasis, CutaneousApoptosisHumansMacrophagesPhagocytosisAnnexin A1

Identifiers

PMID34431955
PMCPMC8405212
OpenAlexW3194891254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.