Evidence map›Paper›PMID 34431550›Full record

ArticleMagnetic resonance in medicine2021

Noninvasive quantification of cerebrovascular pressure changes using 4D Flow MRI.

David Marlevi, Jonas Schollenberger, Maria Aristova, Edward Ferdian, Yue Ma, Alistair A Young, Elazer R Edelman, Susanne Schnell, C Alberto Figueroa, David A Nordsletten

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Inverse problems in blood flow modeling: A review.International journal for numerical methods in biomedical engineering · 2022
    Review
  14. On the numerical treatment of viscous and convective effects in relative pressure reconstruction methods.International journal for numerical methods in biomedical engineering · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David MarleviInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0003-1002-2070
Jonas SchollenbergerDepartment of Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-9245-3984
Maria AristovaDepartment of Radiology, Northwestern University, Chicago, IL, USA.
Edward FerdianDepartment of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand.
Yue MaDepartment of Radiology, Northwestern University, Chicago, IL, USA.
Alistair A YoungDepartment of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand.
Elazer R EdelmanInstitute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Susanne SchnellDepartment of Radiology, Northwestern University, Chicago, IL, USA.
C Alberto FigueroaDepartment of Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
David A NordslettenDepartment of Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.

Funding

Vascular Drug Delivery - Supplement for EquipmentR01GM049039 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI EDELMAN, ELAZER R · 1994 to 2019
$8.9M
Non-invasive Evaluation of Intracranial Atherosclerotic Disease Using Hemodynamic BiomarkersR01HL149787 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ANSARI, SAMEER A, MARKL, MICHAEL · 2020 to 2023
$1.9M
The Role of Aortic-Carotid Hemodynamics and Aberrant Flow in HIV Cerebral InjuryR21NS122511 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAGIN, ANN B, SCHNELL, SUSANNE · 2020 to 2021
$438k
4D Flow MRI for characterization of brain arteriovenous malformationsF30HL140910 · NHLBI · NORTHWESTERN UNIVERSITY · PI ARISTOVA, MARIA · 2018 to 2021
$181k
NHLBI NIH HHS F30 HL140910NHLBI NIH HHS R01 HL149787NIGMS NIH HHS R01 GM049039NINDS NIH HHS R21 NS122511Wellcome Trust
6 · The paper itself

Abstract

purposeHemodynamic alterations are indicative of cerebrovascular disease. However, the narrow and tortuous cerebrovasculature complicates image-based assessment, especially when quantifying relative pressure. Here, we present a systematic evaluation of image-based cerebrovascular relative pressure mapping, investigating the accuracy of the routinely used reduced Bernoulli (RB), the extended unsteady Bernoulli (UB), and the full-field virtual work-energy relative pressure (

methodsPatient-specific in silico models were used to generate synthetic cerebrovascular 4D Flow MRI, with RB, UB, and

resultsThe in silico analysis indicate that accurate relative pressure estimations are inherently coupled to spatial sampling: at dx = 1.0 mm high errors are reported for all methods; at dx = 0.5 mm

conclusionImage-based full-field methods such as

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingBlood Flow VelocityComputer SimulationHealthy VolunteersHemodynamicsHumans4D Flow MRIcerebrovascularhemodynamicspatient-specific modelingrelative pressure

Identifiers

PMID34431550
PMCPMC11421438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.