Evidence map›Paper›PMID 34431330›Full record

ArticleJournal of the American Heart Association2021

Lp(a)-Associated Oxidized Phospholipids in Healthy Black and White Participants in Relation to apo(a) Size, Age, and Family Structure.

Lars Berglund, Kyoungmi Kim, Wei Zhang, Nishant Prakash, Kevin Truax, Erdembileg Anuurad, Byambaa Enkhmaa

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  11. Journal of the American Heart Association · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lars BerglundDepartment of Internal Medicine University of California Davis Davis CA.
Kyoungmi KimDepartment of Public Health Sciences University of California Davis Davis CA.
Wei ZhangDepartment of Internal Medicine University of California Davis Davis CA.
Nishant PrakashDepartment of Internal Medicine University of California Davis Davis CA.ORCID 0000-0003-3621-5591
Kevin TruaxDepartment of Internal Medicine University of California Davis Davis CA.
Erdembileg AnuuradOffice of Research School of Medicine University of California Davis Davis CA.
Byambaa EnkhmaaDepartment of Internal Medicine University of California Davis Davis CA.ORCID 0000-0002-1429-6864
University of California, Davis · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Regulation of Lipoprotein(a) Metabolism in Humans with Reference to EthnicityR01HL062705 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI BERGLUND, LARS F · 2000 to 2011
$2.9M
NCATS NIH HHS UL1 TR001860NHLBI NIH HHS R01 HL062705
6 · The paper itself

Abstract

Background Lp(a) (lipoprotein(a)) is the major lipoprotein carrier of oxidized phospholipids (OxPL) and this function mediates Lp(a) atherogenicity. However, the relationship between OxPL, Lp(a), and genetic and biological characteristics remains poorly understood. We assessed the relationship between Lp(a)-bound OxPL, apolipoprotein(a) (apo(a)) size, age, and family structure in 2 racial groups. Methods and Results Healthy Black and White families were recruited from the general population (age: 6-74 years, n=267). OxPL and Lp(a) levels were assayed enzymatically; apo(a) isoform,

Indexed as

Lipoprotein(a)PhospholipidsAdolescentAdultAgedApoprotein(a)Black PeopleChildHumansMiddle AgedOxidation-ReductionWhite PeopleYoung AdultApoprotein(a)Lipoprotein(a)Phospholipidschildrengeneral populationoxidized lipidsparentsrace

Identifiers

PMID34431330
PMCPMC8649226
OpenAlexW3193419377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.