Evidence map›Paper›PMID 34431245›Full record

ArticleKorean journal of radiology2021

Quantitative Evaluation of Gastrocnemius Medialis Stiffness During Passive Stretching Using Shear Wave Elastography in Patients with Parkinson's Disease: A Prospective Preliminary Study.

Lu Yin, Lijuan Du, Yuanzi Li, Yang Xiao, Shiquan Zhang, Huizi Ma, Wen He

Registry-linked trialAbstract read
In one paragraph

Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06701318 (Ultrasound Shear Wave Elastography for Assessing Muscle Stiffness in Parkinson's Disease Patients), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06701318 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Ultrasound Shear Wave Elastography for Assessing Muscle Stiffness in Parkinson's Disease Patients

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled68ConditionsParkinson DiseaseArmsUltrasound shear wave elastography
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Intraoperative shear wave elastography during surgical treatment of intramedullary spinal cord tumors.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu YinDepartment of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0357-2595
Lijuan DuDepartment of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0153-6136
Yuanzi LiDepartment of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-2468-2988
Yang XiaoInstitute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0002-0516-0543
Shiquan ZhangInstitute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0003-3747-0842
Huizi MaCenter for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-3845-8020
Wen HeDepartment of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. ttyyus@sina.com.ORCID 0000-0002-7177-4498

Funding

BMSTC Z201107001012140NSFC 81730050
6 · The paper itself

Abstract

objectiveTo prospectively investigate the feasibility of shear wave elastography (SWE) as a new quantitative and objective method for evaluating the stiffness of the gastrocnemius medialis (GM) muscle during passive stretching in patients with Parkinson's disease (PD). MATERIALS AND

methodsSWE of the GM muscle was performed in 28 patients with PD [13 female and 15 male; mean age ± standard deviation (SD): 63.0 ± 8.5 years] and 12 healthy controls (5 female and 7 male; mean age ± SD: 59.3 ± 6.4 years) during passive ankle rotation. A Young's modulus-ankle angle curve was constructed. The GM slack angle and baseline Young's modulus (

resultsThe GM slack angle was smaller on both the markedly and mildly symptomatic sides in patients with PD than in healthy controls (mean ± SD of -29.13° ± 3.79° and -25.65° ± 3.39°, respectively, vs. -21.22° ± 3.52°;

conclusionThe slack angle determined by SWE may be a useful quantitative and reproducible method for evaluating muscle stiffness in patients with PD.

Indexed as

Elasticity Imaging TechniquesMuscle Stretching ExercisesParkinson DiseaseFemaleHumansMaleProspective StudiesReproducibility of ResultsMuscle stiffnessParkinson's diseaseRigidityShear wave elastographySlack angle

Identifiers

PMID34431245
PMCPMC8546131

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.