Evidence map›Paper›PMID 34430921›Full record

ArticleSTAR protocols2021

Protocols for electrophysiological recordings and electron microscopy at

Haowen Liu, Lei Li, Mia Krout, Seema Sheoran, Qihong Zhao, Jingyi Chen, Huisheng Liu, Janet E Richmond, Zhitao Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Neuroendocrine Control of Synaptic Transmission by PHAC-1 inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Haowen LiuQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research (CJCADR), The University of Queensland, Brisbane QLD, 4072, Australia.
Lei LiQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research (CJCADR), The University of Queensland, Brisbane QLD, 4072, Australia.
Mia KroutDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Seema SheoranDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Qihong ZhaoQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research (CJCADR), The University of Queensland, Brisbane QLD, 4072, Australia.
Jingyi ChenGuangzhou Laboratory, Guangzhou, Guangdong, China.
Huisheng LiuGuangzhou Laboratory, Guangzhou, Guangdong, China.
Janet E RichmondDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Zhitao HuQueensland Brain Institute, Clem Jones Centre for Ageing Dementia Research (CJCADR), The University of Queensland, Brisbane QLD, 4072, Australia.
The University of Queensland · AUUniversity of Illinois Chicago · USGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CN

Funding

Selective Optogenetic Inhibition of Neuropeptide ReleaseR21EY029450 · NEI · TEL AVIV UNIVERSITY · PI BLINDER, PABLO, HU, ZHITAO · 2018 to 2019
$322k
NEI NIH HHS R21 EY029450
6 · The paper itself

Abstract

Release of neurotransmitters by synaptic vesicle exocytosis at presynaptic terminals is critical for neuronal communication within the nervous system. Electrophysiology and electron microscopy are powerful and complementary approaches used to evaluate the function of synaptic proteins in synaptic transmission. Here, we provide a protocol detailing the use of these two approaches at

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsElectrophysiological PhenomenaMicroscopy, ElectronNeuromuscular JunctionNeuronsPresynaptic TerminalsSynaptic TransmissionCaenorhabditis elegans ProteinsMicroscopyModel OrganismsNeuroscience

Identifiers

PMID34430921
PMCPMC8371263
OpenAlexW3195758387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.