Evidence map›Paper›PMID 34430915›Full record

ArticleSTAR protocols2021

Masahiro Yasuda, Sivapratha Nagappan-Chettiar, Hisashi Umemori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Activity-Dependent Synapse Refinement: From Mechanisms to Molecules.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Masahiro YasudaDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Sivapratha Nagappan-ChettiarDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Hisashi UmemoriDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Boston Children's Hospital · US

Funding

How do neurons in the brain decide to refine their synaptic connections in vivo?R01MH111647 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI Chinfei Chen, Hisashi Umemori · 2017 to 2026
$6.8M
Activity-Dependent Synapse Refinement in the Memory Circuit in vivoR01MH091429 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI UMEMORI, HISASHI · 2010 to 2014
$2.0M
NIMH NIH HHS R01 MH091429NIMH NIH HHS R01 MH111647
6 · The paper itself

Abstract

The visual system is the best system to study activity-dependent sensory circuit development. The connections from the retina to the dorsal lateral geniculate nucleus, the retinogeniculate connections, undergo extensive remodeling during early postnatal life. Thus, techniques that allow the expression of transgenes early in the developing retina are essential to study visual system development. Here, we describe a protocol to express genes-of-interest in the developing mouse retina via

Indexed as

AnimalsDependovirusFetusGene ExpressionGene Expression ProfilingGene Expression Regulation, DevelopmentalInjections, IntraocularMiceRetinaSynapsesTranscriptomeTransgenesVisual Pathwaysdevelopmental biologygene expressionmodel organismsmolecular biologyneuroscience

Identifiers

PMID34430915
PMCPMC8369063
OpenAlexW3195872196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.