ArticleEClinicalMedicine2021
Type 1 diabetes onset in Lombardy region, Italy, during the COVID-19 pandemic: The double-wave occurrence.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Incidence of Diabetes in Children and Adolescents During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Incidence of diabetic ketoacidosis during COVID-19 pandemic: a meta-analysis of 124,597 children with diabetes.Pediatric research · 2023Pooled it
- Pooled it
- Impact of the COVID-19 Pandemic on Children and Adolescents with New-Onset Type 1 Diabetes.Pediatric diabetes · 2023Pooled it
- The global impact of COVID-19 pandemic on the incidence of pediatric new-onset type 1 diabetes and ketoacidosis: A systematic review and meta-analysis.Journal of medical virology · 2022Pooled it
- Incidence of Diabetic Ketoacidosis Among Pediatrics With Type 1 Diabetes Prior to and During COVID-19 Pandemic: A Meta-Analysis of Observational Studies.Frontiers in endocrinology · 2022Pooled it
- Increasing incidence and clinical burden of paediatric type 1 diabetes in Italy: insights from a large administrative database.Acta diabetologica · 2026Article
- COVID-19 outbreak on the seasonality and incidence of pediatric type 1 diabetes mellitus.World journal of diabetes · 2026Article
- Type 1 diabetes incidence during COVID-19 pandemic has not been influenced by COVID-19 vaccination in northern Italy region, Lombardy.PloS one · 2025Article
- Case Report: Usefulness, effectiveness, and safety of an advanced hybrid closed-loop system in a child with early identification of type 1 diabetes.Frontiers in endocrinology · 2025Article
- The COVID-19 Pandemic Increased the Incidence of New-Onset Type One Diabetes in Children.Children (Basel, Switzerland) · 2024Article
- New-onset type 1 diabetes mellitus in the Paediatric Emergency Department: impact of the COVID-19 pandemic.Annals of pediatric endocrinology & metabolism · 2023Article
- Endocrinological Involvement in Children and Adolescents Affected by COVID-19: A Narrative Review.Journal of clinical medicine · 2023Review
- Pediatric COVID-19 and Diabetes: An Investigation into the Intersection of Two Pandemics.Diagnostics (Basel, Switzerland) · 2023Review
- Increased incidence of type 1 diabetes in 2 years of COVID-19 pandemic.Acta diabetologica · 2023Article
- Multiple influences of the COVID-19 pandemic on children with diabetes: Changes in epidemiology, metabolic control and medical care.World journal of diabetes · 2023Review
- Pediatric Diabetes and Diabetic Ketoacidosis After COVID-19: Challenges Faced and Lessons Learnt.Pediatric health, medicine and therapeutics · 2023Review
- Prevalence of type 1 and type 2 diabetes in children and adolescents in Germany from 2002 to 2020: A study based on electronic health record data from the DPV registry.Journal of diabetes · 2022Article
- COVID-19 and diabetes in children.Annals of pediatric endocrinology & metabolism · 2022Article
- Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain.Journal of clinical medicine · 2022Article
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Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Italian Lombardy region has been the epicenter of COVID-19 since February 2020. This study analyses the epidemiology of pediatric type 1 diabetes (T1D) onset during the first two pandemic waves and three previous years.
methodsAll the 13 pediatric diabetes centers in Lombardy prospectively evaluated charts of children at T1D onset (0-17 years), during year 2020. After calculating the annual incidence, the data were compared with those of the 3 previous years, using generalized linear models, adjusted for age and sex. Monthly T1D new onsets and diabetic ketoacidosis (DKA) were investigated yearly from 2017 to 2020. Data were extracted from outpatients charts of the pediatric diabetes centers and from the database of the national institute of statistics.
findingsThe estimated incidence proportion of T1D was 16/100·000 in 2020, compared to 14, 11 and 12 in 2019, 2018 and 2017, respectively. When adjusting for age and gender, the incidence was significantly lower in 2018 and 2017 compared to 2020 (adjusted incidence ratio: 0.73 and 0.77 respectively, with 95% CI: 0.63 to 0.84, and 0.67 to 0.83;
interpretationThe study suggests an increase in the incidence of pediatric T1D in Lombardy throughout the past five years. Pandemic waves may have affected the clinical presentation at onset.
fundingNone.
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