Evidence map›Paper›PMID 34430802›Full record

ArticleACS applied bio materials2021

Scanning Ion Conductance Microscopy Study Reveals the Disruption of the Integrity of the Human Cell Membrane Structure by Oxidative DNA Damage.

Alberto S Rubfiaro, Pawlos S Tsegay, Yanhao Lai, Emmanuel Cabello, Mohammad Shaver, Joshua Hutcheson, Yuan Liu, Jin He

Open access · greenAbstract read
In one paragraph

Article in ACS applied bio materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Scanning ion conductance microscopy reveals differential effect of PMAnalytical and bioanalytical chemistry · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alberto S RubfiaroPhysics Department, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0002-5278-4906
Pawlos S TsegayBiochemistry Ph.D. Program, Florida International University, Miami, Florida 33199, United States.
Yanhao LaiDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.
Emmanuel CabelloPhysics Department, Florida International University, Miami, Florida 33199, United States.
Mohammad ShaverDepartment of Biomedical Engineering, Florida International University, Miami, Florida 33199, United States.
Joshua HutchesonDepartment of Biomedical Engineering and Biomolecular Science Institute, Florida International University, Miami, Florida 33199, United States.
Yuan LiuBiochemistry Ph.D. Program, Department of Chemistry and Biochemistry, and Biomolecular Science Institute, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0003-4797-6396
Jin HePhysics Department and Biomolecular Science Institute, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0002-2633-9809
Florida International University · US

Funding

Trinucleotide Repeat Instability via DNA Damage and RepairR01ES023569 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI LIU, YUAN · 2014 to 2018
$1.6M
NIEHS NIH HHS R01 ES023569
6 · The paper itself

Abstract

Oxidative stress can damage organs, tissues, and cells through reactive oxygen species (ROS) by oxidizing DNA, proteins, and lipids, thereby resulting in diseases. However, the underlying molecular mechanisms remain to be elucidated. In this study, employing scanning ion conductance microscopy (SICM), we explored the early responses of human embryonic kidney (HEK293H) cells to oxidative DNA damage induced by potassium chromate (K

Indexed as

HumansMicroscopyOxidative Stresscell membranechromateoxidative DNA damageoxidative stressscanning ion conductance microscopyβ-actin

Identifiers

PMID34430802
PMCPMC8382241
OpenAlexW3124341951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.