ArticleHeliyon2021
Urinary hippuric acid level as a biological indicator of toluene exposure on batik workers.
Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Kinetic Profile of Urine Metabolites after Acute Intake of a Phenolic Compounds-Rich Juice of Juçara (International journal of molecular sciences · 2023Trial
- Climatic effects on urinary hippuric acid concentrations: a 3-year occupational health study in a manufacturing workforce.Journal of occupational health · 2026Article
- Gut Microbiota Affects Mouse Social Behavior via Hippuric Acid Metabolism.Neurology international · 2025Article
- Structure of Bovine GlycineBiochemistry · 2025Article
- Evaluation of synergistic factors on BTEX urinary biomarkers in motorcycle riders exposed to heavy traffic in a megacity.Scientific reports · 2025Article
- Estimation of micro-extraction process hippuric acid for toluene exposure monitoring in urine samples.Scientific reports · 2025Article
- Investigating the general effects of different types of toluene exposure on the health of workers: an integrative review of the literature.BMJ public health · 2025Article
- Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis.Journal of pediatric gastroenterology and nutrition · 2024Article
- Acute organic solvent toxic encephalopathy: A case report and literature review.Biomedical reports · 2024Article
- Differential Urinary Microbiome and Its Metabolic Footprint in Bladder Cancer Patients Following BCG Treatment.International journal of molecular sciences · 2024Article
- Metabolomic biomarkers in liquid biopsy: accurate cancer diagnosis and prognosis monitoring.Frontiers in oncology · 2024Review
- Deciphering the human urine matrix: a new approach to simultaneously quantify the main ions and organic compounds by ion chromatography/mass spectrometry (IC-MS).Analytical and bioanalytical chemistry · 2023Article
- Disentangling the Complexity of Nutrition, Frailty and Gut Microbial Pathways during Aging: A Focus on Hippuric Acid.Nutrients · 2023Review
- Investigation of dermal exposure to heavy metals (Cu, Zn, Ni, Al, Fe and Pb) in traditional batik industry workers.Heliyon · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urinary hippuric acid (uHA) is one of the biomonitoring parameters of toxic organic exposure, such as toluene. Repeated exposure to a low concentration of toluene may lead to chronic effects such as central nervous system damage. In the preliminary study, toluene was found in the batik industry's working area in Yogyakarta, Indonesia. This study aims to assess the health condition of batik workers to toluene exposure based on the concentration of uHA. There were 52 respondents divided into 2 groups: the batik workers as the exposed group (30 respondents) and the non-batik workers as the control group (22 respondents). The urine sample was taken from batik workers at the end of the shift, and uHA was measured using spectrophotometry. The uHA value was corrected with urinary creatinine. The results showed that the average uHA concentration of batik workers was higher than that of the control group. The result also showed that workers with more than 2 years working period, writing workers, and stamping workers give an Odds Ratio (OR) of 6.43, 6.75, and 9.00 respectively on having a higher concentration of uHA. Workers with toluene exposure symptoms were also having a higher concentration of uHA than workers without any symptoms.
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