Evidence map›Paper›PMID 34430675›Full record

ArticleOpen forum infectious diseases2021

Prevalence of Gastrointestinal Pathogens Detected by Multiplex Polymerase Chain Reaction in a Prospective Cohort of Men Who Have Sex With Men Taking Human Immunodeficiency Virus Preexposure Prophylaxis-New York City, 2019-2020.

Lawrence Purpura, Jason Zucker, Elijah LaSota, Mabel Lopez, Rebecca Spicehandler, Caroline Carnevale, Edward Perez, Paul Richards, Jennifer Chang, Al Cohall and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lawrence PurpuraDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.ORCID https://orcid.org/0000-0002-2900-6022
Jason ZuckerDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.ORCID https://orcid.org/0000-0001-6987-6412
Elijah LaSotaDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Mabel LopezClinical Microbiology, Department of Pathology, Columbia University Irving Medical Center, New York, New York, USA.
Rebecca SpicehandlerDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Caroline CarnevaleNew York Presbyterian-Columbia Hospital, New York, New York, USA.
Edward PerezNew York Presbyterian-Columbia Hospital, New York, New York, USA.
Paul RichardsNew York Presbyterian-Columbia Hospital, New York, New York, USA.
Jennifer ChangDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Al CohallNew York Presbyterian-Columbia Hospital, New York, New York, USA.
Anne-Catrin UhlemannDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Susan WhittierClinical Microbiology, Department of Pathology, Columbia University Irving Medical Center, New York, New York, USA.
Magdalena E SobieszczykDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Daniel A GreenClinical Microbiology, Department of Pathology, Columbia University Irving Medical Center, New York, New York, USA.

Funding

LOC: HIV Vaccine Trials NetworkUM1AI068614 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Dan H. Barouch, Lawrence Corey · 2011 to 2026
$1175.6M
Columbia Partnership for Prevention and Control of HIV/AIDS Clinical Trials UnitUM1AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK · 2012 to 2026
$44.8M
Columbia Collaborative HIV/AIDS Clinical Trials UnitU01AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAMMER, SCOTT M · 2007 to 2011
$15.4M
Global HIV Implementation Science Research Training Grant RenewalT32AI114398 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yael R Hirsch-Moverman · 2014 to 2026
$4.1M
Harnessing Bioinformatics for HIV Prevention: Understanding Persistence in Comprehensive HIV Prevention ServicesK23AI150378 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZUCKER, JASON · 2020 to 2024
$960k
NIAID NIH HHS K23 AI150378NIAID NIH HHS T32 AI114398NIAID NIH HHS U01 AI069470NIAID NIH HHS UM1 AI068614NIAID NIH HHS UM1 AI069470
6 · The paper itself

Abstract

Multiplex polymerase chain reaction testing for gastrointestinal pathogens was performed on a longitudinal cohort of 110 men who have sex with men taking human immunodeficiency virus preexposure prophylaxis. At least 1 pathogen was detected among 50 (45%) participants, with some participants testing positive for the same pathogen on multiple consecutive visits over a period of months.

Indexed as

gastrointestinal pathogenmen who have sex with menpolymerase chain reactionpreexposure prophylaxis

Identifiers

PMID34430675
PMCPMC8379716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.