Evidence map›Paper›PMID 34430496›Full record

ReviewJournal of International Society of Preventive & Community Dentistry

Silver Diamine Fluoride Versus Atraumatic Restorative Treatment in Pediatric Dental Caries Management: A Systematic Review and Meta-analysis.

Tulika Wakhloo, Srinivas Gosla Reddy, Suresh K Sharma, Ashi Chug, Ashutosh Dixit, Kalpana Thakur

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Silver diamine fluoride for non-operative restorative treatment and prevention of dental caries.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. AnBioinformation · 2024
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution.

Tulika WakhlooDepartment of Dentistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Srinivas Gosla ReddyDepartment of Dentistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Suresh K SharmaCollege of Nursing, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Ashi ChugDepartment of Dentistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Ashutosh DixitDepartment of Dentistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Kalpana ThakurCollege of Nursing, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective was to compare the clinical efficacy of silver diamine fluoride (SDF) and atraumatic restorative treatment (ART) in arresting active caries in primary teeth and first permanent molars in children. MATERIALS AND

methodsThe study protocol was registered in PROSPERO (CRD42020205675). A systematic search was performed in PubMed, Scopus, Embase, Cochrane Library, and gray literature for randomized controlled trials (RCTs) published in English language with a minimum follow-up of 6 months, comparing the caries arrest potential of SDF with ART in primary teeth and first permanent molars in children. The risk of bias and quality assessment of the studies was done using the Cochrane Collaboration Tool and Joanna Briggs Institute Critical Appraisal Tool. Data analysis was performed using RevMan software; the outcomes were summarized in meta-analysis (MA) using the random-effects model, and the odds ratio (OR) at 95% confidence interval (CI) was computed.

resultsA total of 1059 studies were identified, out of which 562 remained after removal of duplicates. Eight studies were considered for full-text eligibility, and four studies were included in the qualitative review. Three out of four studies were conducted on primary dentition, whereas one study was done on erupting first permanent molars in children. MA of the two studies compared 30% SDF with ART in primary molars at 12 months and revealed the OR to be 2.02 (95% CI: 0.86-4.71;

conclusionThe current review points to the lack of solid evidence comparing SDF with ART for arresting active caries in primary teeth, especially in the first permanent molars. No statistically significant difference between 30% SDF and ART in primary molars at 12 months was found in the present review. Well-designed RCTs are required to determine a minimum concentration of SDF which is effective and safe for caries arrest in children.

Indexed as

Atraumatic restorative treatmentdental caries arrestminimal intervention dentistrynon-aerosol-generating procedurespediatric dentistrysilver diamine fluoride

Identifiers

PMID34430496
PMCPMC8352060
OpenAlexW3188406550

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.