Evidence map›Paper›PMID 34430359›Full record

ArticleTranslational lung cancer research2021

Detection of epidermal growth factor receptor (

Kai Guo, Changjian Shao, Lu Han, Honggang Liu, Zhiqiang Ma, Yang Yang, Yingtong Feng, Minghong Pan, Mariacarmela Santarpia, Maria Carmo-Fonseca and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Translational lung cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Clinical implications of ctDNA for EGFR-TKIs as first-line treatment in NSCLC.Journal of cancer research and clinical oncology · 2023
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 4 countries.

Kai GuoDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Changjian ShaoDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Lu HanDepartment of Ultrasound, Xi'an Central Hospital, Xi'an Jiaotong University, Xi'an, China.
Honggang LiuDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Zhiqiang MaDepartment of Oncology, Chinese PLA General Hospital, Beijing, China.
Yang YangDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yingtong FengDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Minghong PanDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Mariacarmela SantarpiaMedical Oncology Unit, Department of Human Patology "G. Barresi", University of Messina, Messina, Italy.
Maria Carmo-FonsecaInstituto de Medicina Molecular João Lobo Antunes, University of Lisbon Medical School, Lisbon, Portugal.
Catarina SilveiraGenoMed - Molecular Medicine Diagnostics, S.A., Lisbon, Portugal.
Kye Young LeePrecision Medicine Lung Cancer Center, Konkuk University Medical Center, Seoul, Korea.
Jing HanDepartment of Ophthalmology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Xiaofei LiDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Xiaolong YanDepartment of Thoracic Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Air Force Medical University · CNChinese PLA General Hospital · CNKonkuk University Medical Center · KRUniversity of Lisbon · PTUniversity of Messina · ITXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlasma circulating tumor DNA (ctDNA) may be a surrogate, minimally invasive approach to tissue-based epidermal growth factor receptor (

methodsStage I-III NSCLC patients with tissue

resultsPlasma-based ctDNA

conclusions

Indexed as

amplified refractory mutation system (ARMS)epidermal growth factor receptor (EGFR)Non-small cell lung cancer (NSCLC)overall survival and disease-free survival (OS and DFS)preoperative plasma

Identifiers

PMID34430359
PMCPMC8350110
OpenAlexW3183882835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.