Evidence map›Paper›PMID 34430207›Full record

ArticleIDCases2021

Visceral leishmaniasis associated with macrophage activation syndrome: Case report and literature review.

Boutaina Mouhoub, Mohammed Bensalah, Abdelilah Berhili, Ali Azghar, Jalila El Malki, Imane El Mezgueldi, Oumaima Nassiri, Mounia Slaoui, Achraf Miri, Chaymae Rochdi and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Parasitic and Fungal Triggers of Cytokine Storm Syndrome.Advances in experimental medicine and biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Boutaina MouhoubCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Mohammed BensalahCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Abdelilah BerhiliCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Ali AzgharCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Jalila El MalkiCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Imane El MezgueldiCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Oumaima NassiriCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Mounia SlaouiCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Achraf MiriCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Chaymae RochdiCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Noufissa BenajibaFaculty of Medicine and Pharmacy Oujda, Mohammed First University Oujda, Morocco.
Rachid SeddikCentral Laboratory, University Hospital Center Mohamed VI Oujda, Morocco.
Mohamed I University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combination of visceral leishmaniasis (VL) and macrophage activation syndrome (MAS) makes the diagnosis difficult due to their similar clinical presentation, with a poor prognosis especially since the treatment is still poorly codified.We report the case of a 17-month-old female patient from Berkane, presenting for a 3 months history of anarchic fever with anemic syndrome made up of pallor and hemorrhagic syndrome made up of epistaxis. Physical examination revealed a temperature of 39 ° C, lower limbsedema, paleness of skin and mucous membranes, gingival petechiae, bleached hair, and hepatosplenomegaly. CASE PRESENTATION: The complete blood count showed pancytopenia with deep aregenerative normochromic normocytic anemia at 3 g/dL, leukocytes were at 4860/mm 3 with neutropenia at 680/mm 3 and thrombocytopenia at 12.000/mm

conclusionThe association of VL and MAS remains rare and should be evoked even in non-endemic areas since late diagnosis worsens the prognosis and may even be responsible for the death of patients despite an aggressive treatment.

Indexed as

DIC, disseminated intravascular coagulationHLH, Hemophagocytic LymphohistiocytosisLDH, lactate dehydrogenaseMacrophage activation syndromeMAS, macrophage activation syndromeMCH, mean corpuscular hemoglobinMGV, mean globular volumeMoroccoProtozoa parasitePT, prothrombin timeSand fliesVisceral leishmaniasisVL, visceral leishmaniasis

Identifiers

PMID34430207
PMCPMC8371194
OpenAlexW3195496510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.