Evidence map›Paper›PMID 34430203›Full record

ArticleMetabolic engineering communications2021

Engineering

Erika Arvay, Bradley W Biggs, Laura Guerrero, Virginia Jiang, Keith Tyo

Abstract read
In one paragraph

Article in Metabolic engineering communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Genome evolution ofApplied and environmental microbiology · 2025
    Article
  6. Article
  7. Metabolic engineering ofMetabolic engineering communications · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erika ArvayDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.
Bradley W BiggsDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.
Laura GuerreroDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Virginia JiangDepartment of Chemical Engineering, Columbia University, New York, NY, USA.
Keith TyoDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Utilization of lignin, an abundant renewable resource, is limited by its heterogenous composition and complex structure. Biological valorization of lignin provides advantages over traditional chemical processing as it occurs at ambient temperature and pressure and does not use harsh chemicals. Furthermore, the ability to biologically funnel heterogenous substrates to products eliminates the need for costly downstream processing and separation of feedstocks. However, lack of relevant metabolic networks and low tolerance to degradation products of lignin limits the application of traditional engineered model organisms. To circumvent this obstacle, we employed

Indexed as

Acinetobacter baylyi ADP1LigninMetabolic engineeringMevalonateRenewable chemistry

Identifiers

PMID34430203
PMCPMC8367835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.