ArticleMetabolic engineering communications2021
Identification of a lichen depside polyketide synthase gene by heterologous expression in
Article in Metabolic engineering communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Antifungal and Profungal Potentials of Acetone-Extracted Complexes of Lichen Substances on MacromyceteMolecules (Basel, Switzerland) · 2026Article
- Siderophore production by the lichen fungus Xanthoria parietina supports its algal symbiont.Nature communications · 2026Article
- Deciphering the biosynthetic pathways of lichen acids.The New phytologist · 2026Article
- Unveiling Lichen's Hidden Arsenal Against Multidrug Resistance: A Systematic Review of Their Essential Oils, Volatile Compounds and Extracts with Antimicrobial Applications.Microorganisms · 2026Review
- Paired-omics-based exploration and characterization of biosynthetic diversity in lichenized fungi.Microbial genomics · 2025Article
- The Role of Nucleotide Sequencing in Natural Product Drug Discovery.Journal of natural products · 2025Review
- A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont.Environmental microbiology · 2025Article
- Functional heterologous expression of the reversibleEngineering microbiology · 2025Article
- Breaking into nature's secret medicine cabinet: lichens - a biochemical goldmine ready for discovery.The New phytologist · 2025Review
- Lichens are a treasure chest of bioactive compounds: fact or fake?The New phytologist · 2025Article
- Investigation of Antimicrobial Compounds Produced by Endolichenic Fungi in Different Culture Media.The plant pathology journal · 2024Article
- Discovery and Heterologous Expression of Functional 4-Journal of natural products · 2024Article
- Activation of secondary metabolite gene clusters in Chaetomium olivaceum via the deletion of a histone deacetylase.Applied microbiology and biotechnology · 2024Article
- Assessment of the photoprotective potential and structural characterization of secondary metabolites of Antarctic fungus Arthrinium sp.Archives of microbiology · 2023Article
- Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata.MicrobiologyOpen · 2023Article
- Biosynthetic Potential ofJournal of fungi (Basel, Switzerland) · 2023Article
- Metagenomics Shines Light on the Evolution of "Sunscreen" Pigment Metabolism in the Teloschistales (Lichen-Forming Ascomycota).Genome biology and evolution · 2023Article
- Linking Lichen Metabolites to Genes: Emerging Concepts and Lessons from Molecular Biology and Metagenomics.Journal of fungi (Basel, Switzerland) · 2023Review
- Tridepsides as potential bioactives: a review on their chemistry and the global distribution of their lichenic and non-lichenic natural sources.Frontiers in fungal biology · 2023Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lichen-forming fungi produce a variety of secondary metabolites including bioactive polyketides. Advances in DNA and RNA sequencing have led to a growing database of new lichen gene clusters encoding polyketide synthases (PKS) and associated ancillary activities. Definitive assignment of a PKS gene to a metabolic product has been challenging in the lichen field due to a lack of established gene knockout or heterologous gene expression systems. Here, we report the reconstitution of a non-reducing PKS gene from the lichen
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