Evidence map›Paper›PMID 34430172›Full record

ArticleCureus2021

Hepatocellular Carcinoma in a Patient With Crohn's Disease.

Akira Hokama, Shingo Arakaki, Shinichiro Ishino, Yutaka Nakagawa, Souhei Tabata, Daiki Agarie, Satoshi Kuwae, Ryuta Zukeyama, Tatsuji Maeshiro, Yuma Tsuruta and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Akira HokamaDepartment of Endoscopy, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Shingo ArakakiDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Shinichiro IshinoDepartment of General and Digestive Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Yutaka NakagawaDepartment of General and Digestive Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Souhei TabataDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Daiki AgarieDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Satoshi KuwaeDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Ryuta ZukeyamaDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Tatsuji MaeshiroDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Yuma TsurutaDepartment of Pathology, University of the Ryukyus Hospital, Nishihara, JPN.
Akiko MatsuzakiDepartment of Pathology, University of the Ryukyus Hospital, Nishihara, JPN.
Naoki WadaDepartment of Pathology and Oncology, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Mitsuhisa TakatsukiDepartment of General and Digestive Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.
Jiro FujitaDepartment of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 44-year-old woman with a 26-year history of Crohn's disease (CD) presented with intermittent fever, vomiting, and watery diarrhea. Her medication included an elemental diet, mesalazine, and infliximab. Liver profile and viral hepatitis markers were normal. Computed tomography scans showed a hepatic tumor by chance. Serum tumor markers disclosed elevated protein induced by vitamin K absence-II. With a diagnosis of hepatocellular carcinoma (HCC), she underwent a hepatic resection of the tumor, revealing well-to-moderately differentiated HCC. The nontumor region of the liver disclosed the absence of cirrhosis or other diseases. Here, the development of HCC in CD without underlying liver diseases is discussed with a review of the literature.

Indexed as

computed tomographycrohn’s disease (cd)hepatocellular carcinomainfliximabpathology

Identifiers

PMID34430172
PMCPMC8378283

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.