Evidence map›Paper›PMID 34430118›Full record

ArticleCureus2021

Thyroid Storm-Induced Acute Liver Dysfunction and Disseminated Intravascular Coagulation.

Yungmin Kim, Dawa Gurung, Vikram Sumbly, David M Reich, Tayyaba Bashir

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yungmin KimInternal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Dawa GurungInternal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Vikram SumblyInternal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
David M ReichMedicine/Endocrinology, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Tayyaba BashirHematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid storm-induced disseminated intravascular coagulation (DIC) is a very rare complication of untreated/undertreated Graves' disease. It is considered to be a medical emergency as it can rapidly lead to hemodynamic instability in patients due to multi-organ failure. Although the exact pathogenesis of this hematological phenomenon remains poorly understood, it is believed to be triggered by the uncontrolled release of pro-inflammatory cytokines, which in turn prematurely activates the coagulation cascade. In this report, we present the case of a 48-year-old female who presented with symptoms of abdominal pain, dyspnea, and unintentional weight loss for the past several weeks. Her vital signs, overall clinical picture, and laboratory tests confirmed thyroid storm complicated by DIC and acute liver injury. The patient made a significant recovery after the initiation of methimazole therapy.

Indexed as

disseminated intravascular coagulationgraves diseasehepatitisthrombocytopeniathyrotoxicosis

Identifiers

PMID34430118
PMCPMC8375274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.