Evidence map›Paper›PMID 34430108›Full record

ArticleCureus2021

Cryptococcal Meningitis Causing Refractory Hemichorea-Hemiballismus Treated With Pallidotomy.

Kevin G Buell, Brian P Vickers, Karen C Bloch, Amy E Brown, Peter Hedera, Walter Jermakowicz, Peter E Konrad, E Wesley Ely

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Rescue Pallidotomy for Chorea Paralytica.Movement disorders clinical practice · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin G BuellDepartment of Medicine, Vanderbilt University Medical Center, Nashville, USA.
Brian P VickersDepartment of Medicine, Vanderbilt University Medical Center, Nashville, USA.
Karen C BlochDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, USA.
Amy E BrownDepartment of Neurology, Vanderbilt University Medical Center, Nashville, USA.
Peter HederaDepartment of Neurology, University of Louisville, Louisville, USA.
Walter JermakowiczDepartment of Neurosurgery, Vanderbilt University Medical Center, Nashville, USA.
Peter E KonradDepartment of Neurosurgery, Vanderbilt University Medical Center, Nashville, USA.
E Wesley ElyCritical Illness, Brain Dysfunction, and Survivorship (CIBS) Center; and Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 31-year-old immunocompetent male who presented with altered mental status and agitation requiring intubation. As sedation was weaned, he demonstrated choreiform movements with associated hemiballismus of the right upper and lower extremities, and he was ultimately diagnosed with cryptococcal meningitis. The patient's chorea did not terminate after the completion of induction antifungal therapy and all pharmacologic options for the management of chorea were ineffective. He underwent a successful unilateral pallidotomy using standard stereotactic methodology targeting the posterior-ventral pallidum, and his choreiform movements dramatically improved post-operatively within 48 hours.

Indexed as

cryptococcal meningitiscryptococcus neoformanshemiballismushemichoreapallidotomy

Identifiers

PMID34430108
PMCPMC8372680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.