Evidence map›Paper›PMID 34430080›Full record

ArticlePeerJ2021

Potential

Sarahani Harun, Nor Afiqah-Aleng, Mohammad Bozlul Karim, Md Altaf Ul Amin, Shigehiko Kanaya, Zeti-Azura Mohamed-Hussein

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Plant direct · 2026
    Article
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sarahani HarunCentre for Bioinformatics Research, Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia.
Nor Afiqah-AlengInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia.
Mohammad Bozlul KarimGraduate School of Science and Technology & NAIST Data Science Center, Nara Institute of Science and Technology, Nara, Japan.
Md Altaf Ul AminGraduate School of Science and Technology & NAIST Data Science Center, Nara Institute of Science and Technology, Nara, Japan.
Shigehiko KanayaGraduate School of Science and Technology & NAIST Data Science Center, Nara Institute of Science and Technology, Nara, Japan.
Zeti-Azura Mohamed-HusseinCentre for Bioinformatics Research, Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia.ORCID 0000-0002-5386-7260
Nara Institute of Science and Technology · JPNational University of Malaysia · MYUniversiti Malaysia Terengganu · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlucosinolates (GSLs) are plant secondary metabolites that contain nitrogen-containing compounds. They are important in the plant defense system and known to provide protection against cancer in humans. Currently, increasing the amount of data generated from various omics technologies serves as a hotspot for new gene discovery. However, sometimes sequence similarity searching approach is not sufficiently effective to find these genes; hence, we adapted a network clustering approach to search for potential GSLs genes from the

methodsWe used known GSL genes to construct a comprehensive GSL co-expression network. This network was analyzed with the DPClusOST algorithm using a density of 0.5. 0.6. 0.7, 0.8, and 0.9. Generating clusters were evaluated using Fisher's exact test to identify GSL gene co-expression clusters. A significance score (SScore) was calculated for each gene based on the generated

resultsThe density value of 0.8 showed the highest area under the curve (AUC) leading to the selection of thirteen potential GSL genes from the top six significant clusters that include

Indexed as

Aliphatic glucosinolatesGene network analysisGraph clusteringIndolic glucosinolatesNitrogen-containing compoundsSecondary metabolites

Identifiers

PMID34430080
PMCPMC8349163
OpenAlexW3188861300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.