ArticleDental research journal2021
Evaluation the relationship between psychological profile and salivary cortisol in patients with recurrent aphthous stomatitis.
Article in Dental research journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Psychological factors and quality of life in oral mucosal diseases: A systematic review of assessment tools and clinical implications.BMC oral health · 2026Pooled it
- Prevalence of oral recurrent aphthous stomatitis and its association with stress among a sample of Egyptian dental students: a cross-sectional study.Head & face medicine · 2026Article
- Interrelationships Among Psychological Conditions, Oral Health-related Quality of Life, and Clinical Characteristics in Chinese Patients with Minor Recurrent Aphthous Stomatitis.International dental journal · 2026Article
- Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study.BMC oral health · 2025Article
- Oral mucosal diseases and psychosocial factors: progress in related neurobiological mechanisms.The Journal of international medical research · 2023Review
- A case-control investigation of the psychological and physiological stress markers with salivary cortisol levels in patients with temporomandibular joint disorders: A short clinical study.Journal of Indian Prosthodontic SocietyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecurrent aphthous stomatitis (RAS) is one of the most common oral mucosal diseases which are diagnosed with recurrent and painful ulcers. The possible association between psychological factors and salivary stress related factors in patients with aphthous ulcers has been discussed in various studies. The aim of this study was to evaluate salivary cortisol level, anxiety, and depression in patients with RAS. MATERIALS AND
methodsIn this case control study, 30 patients with RAS and 30 healthy individuals were enrolled by matching their age and sex. Anxiety and depression were assessed by beck anxiety inventory and beck depression inventory. Unstimulated saliva of both groups were collected and then tested by DiaMetra kit and the ELISA method. Data were analyzed by SPSS using an Independent
resultsThe mean salivary cortisol in the case group was 5.35 ng/ml and in the control group was 4.73 ng/ml which was not statistically significant (
conclusionThis study shows that, although the mean salivary cortisol was slightly higher in patients with aphthous lesions, anxiety, and depression were not possible factors for RAS. There was a moderate, negative correlation between salivary cortisol level and stress and anxiety in patients with RAS.
Indexed as
Identifiers
34429870PMC8351933W3177358249What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.