Evidence map›Paper›PMID 34429633›Full record

ArticlePharmacogenomics and personalized medicine2021

Long Non-Coding RNAs Gene Variants as Molecular Markers for Diabetic Retinopathy Risk and Response to Anti-VEGF Therapy.

Hala M F Mohammad, Ahmed A Abdelghany, Essam Al Ageeli, Shahad W Kattan, Ranya Hassan, Eman A Toraih, Manal S Fawzy, Naglaa Mokhtar

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Non-coding RNA research · 2024
    Review
  5. Review
  6. Noncoding RNA Contribution to Aging and Lifespan.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Prognostic Value ofBiomolecules · 2022
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Hala M F MohammadDepartment of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0002-1349-5300
Ahmed A AbdelghanyDepartment of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0001-5785-3192
Essam Al AgeeliDepartment of Clinical Biochemistry (Medical Genetics), Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.ORCID 0000-0002-6625-6012
Shahad W KattanDepartment of Medical Laboratory, College of Applied Medical Sciences, Taibah University, Yanbu, Saudi Arabia.ORCID 0000-0002-7151-3845
Ranya HassanDepartment of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0001-7178-1965
Eman A ToraihDepartment of Surgery, Tulane University, School of Medicine, New Orleans, LA, USA.ORCID 0000-0001-9267-3787
Manal S FawzyDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0003-1252-8403
Naglaa MokhtarDepartment of Biochemistry, Faculty of Medicine, Northern Border University, Arar, Saudi Arabia.ORCID 0000-0002-8364-1238
Suez Canal University · EGJazan University · SANorthern Border University · SATaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNAs (lncRNAs) play essential roles in molecular diagnosis and therapeutic response in several diseases. PURPOSE: For the first time, we aimed to evaluate the association of four lncRNAs PATIENTS AND

methodsThis case-control study enrolled 126 adult patients with type 2 diabetes. TaqMan assays using Real-Time PCR were run for genotyping. Multivariable regression analyses were applied to assess the role of each polymorphism after the adjustment of covariates.

resultsCarriers of

conclusionThe lncRNAs

Indexed as

afliberceptdiabetic retinopathyMALAT1MIATSENCRTUG1

Identifiers

PMID34429633
PMCPMC8374537
OpenAlexW3195089878

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.