Evidence map›Paper›PMID 34429620›Full record

ReviewInfection and drug resistance2021

Understanding Factors in Group B Streptococcus Late-Onset Disease.

Alberto Berardi, Viola Trevisani, Antonella Di Caprio, Jenny Bua, Mariachiara China, Barbara Perrone, Rossella Pagano, Laura Lucaccioni, Silvia Fanaro, Lorenzo Iughetti and 2 more

Abstract readReview
In one paragraph

Review in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. CRISPR interference in aJournal of bacteriology · 2026
    Article
  5. Article
  6. Group BAJP reports · 2026
    Article
  7. Article
  8. Article
  9. Identification of glyoxalase A in group BInfection and immunity · 2025
    Article
  10. Article
  11. Article
  12. Identification of Glyoxalase A in Group BbioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. [Recent research on the epidemiology and preventive strategies of neonatal group BZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  17. Strategies to Prevent Early and Late-Onset Group BPathogens (Basel, Switzerland) · 2023
    Review
  18. Article
  19. Updates on Group BMicroorganisms · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alberto BerardiTerapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.ORCID 0000-0002-3534-7499
Viola TrevisaniScuola di Specializzazione in Pediatria, Università di Modena & Reggio Emilia, Modena, Italy.
Antonella Di CaprioScuola di Specializzazione in Pediatria, Università di Modena & Reggio Emilia, Modena, Italy.
Jenny BuaTerapia Intensiva Neonatale, IRCCS Azienda Ospedaliero Universitaria "Burlo Garofalo", Trieste, Italy.
Mariachiara ChinaTerapia Intensiva Neonatale, Ospedale Infermi, Rimini, Italy.
Barbara PerroneTerapia Intensiva Neonatale, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, Italy.
Rossella PaganoUnità Operativa di Pediatria, Civile Sassuolo, Sassuolo, Italy.
Laura LucaccioniUnità Operativa di Pediatria, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.
Silvia FanaroTerapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria S. Anna, Ferrara, Italy.
Lorenzo IughettiScuola di Specializzazione in Pediatria, Università di Modena & Reggio Emilia, Modena, Italy.
Licia LugliTerapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.
Roberta CretiReparto di Antibiotico Resistenza e Patogeni Speciali (AR-PS), Dipartimento di Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group B streptococcus (GBS) infection remains a leading cause of sepsis, pneumonia, and meningitis in infants. Rates of GBS early onset disease have declined following the widcespread use of intrapartum antibiotic prophylaxis; hence, late-onset infections (LOGBS) are currently a common presentation of neonatal GBS dicsease. The pathogenesis, mode of transmission, and risk factors associated with LOGBS are unclear, which interfere with effective prevention efforts. GBS may be transmitted from the mother to the infant at the time of delivery or during the postpartum period via contaminated breast milk, or as nosocomial or community-acquired infection. Maternal GBS colonization, prematurity, young maternal age, HIV exposure, and ethnicity (Black) are identified as risk factors for LOGBS disease; however, further studies are necessary to confirm additional risk factors, if any, for the implementation of effective prevention strategies. This narrative review discusses current and previous studies that have reported LOGBS. Few well-designed studies have described this condition; therefore, reliable assessment of maternal GBS colonization, breastfeeding, and twin delivery as risk factors for LOGBS remains limited.

Indexed as

CC17infantmeningitisneonatal sepsisprevention

Identifiers

PMID34429620
PMCPMC8380284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.