Evidence map›Paper›PMID 34429586›Full record

ArticleDrug design, development and therapy2021

The Clinical Efficacy of Three Different Follicle-Stimulating Hormones for Follicle Growth and Development in Long-Protocol Controlled Ovarian Hyperstimulation Treatment.

Xi-Qian Zhang, Li-Jia Zhang, Xiu-Lan Zhu, Hong Xu, Yan-Qun Luo, Li Yao, Qian-Wen Huang, Ying-Qi Nong, Wen-Juan Liu, Feng-Hua Liu

Open access · goldAbstract readComparative Study
In one paragraph

Article in Drug design, development and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xi-Qian Zhang *Reproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Li-Jia Zhang *Reproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Xiu-Lan ZhuReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Hong XuReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Yan-Qun LuoReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Li YaoReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Qian-Wen HuangReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Ying-Qi NongReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Wen-Juan LiuReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Feng-Hua LiuReproductive Medical Center, Guangdong Women and Children Hospital, Guangzhou, 511442, People's Republic of China.
Guangdong Province Women and Children Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the use and clinical efficacy of three different follicle-stimulating hormones (FSHs) for follicle growth and development in long-protocol controlled ovarian hyperstimulation (COH).

methodsA total of 540 gonadotropin-releasing hormone (GnRH) agonists' long protocol treatment cycles at our hospital between January 2015 and May 2020 and met the inclusion criteria were retrospectively analyzed. The cycles were divided into three groups based on their indexes (groups A, B, and C). Each of the groups received a different type of FSH during treatment. A cross-group comparison was then undertaken to evaluate the growth and development of the three largest follicles and the patients' pregnancy-related indexes between the normal-response and high-response populations.

resultsIn the normal-response populations, the number of high-quality embryos obtained in groups A and B was significantly higher than in group C, and the FSH dosage was significantly lower than in group C (

conclusionThree different types of FSH led to comparable growth rates of the three largest follicles and clinical pregnancy rates per fresh cycle in long-protocol COH treatment.

Indexed as

AdultDose-Response Relationship, DrugFemaleFollicle Stimulating HormoneHumansOocytesOvarian FollicleOvulation InductionPregnancyPregnancy RateRetrospective StudiesTime FactorsTreatment OutcomeFollicle Stimulating Hormonefollicle distribution on hCG dayfollicle growth ratefollicle-stimulating hormoneGn stimulation durationhigh-quality embryos

Identifiers

PMID34429586
PMCPMC8378929
OpenAlexW3195067355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.