ArticleNature immunology2021
Insulin signaling establishes a developmental trajectory of adipose regulatory T cells.
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Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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61citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
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Who cites it
61 citing papers in PubMed, 89 citations in OpenAlex.
- The Mediator complex: co-transcriptional regulation and beyond.RNA biology · 2026Review
- Beyond immune suppression: regenerative programs in regulatory T cells.Cell insight · 2026Review
- Palmitic acid coordinates impaired visceral adipose ICOShi Treg-mediated immunosuppression and systemic metabolic disturbance during obesity.The Journal of clinical investigation · 2026Article
- Hypoxia-Inducible Factor 1α in Type 2 Diabetes Mellitus: Mechanisms and Therapeutic Perspectives.Biology · 2026Review
- Unveiling non-small cell lung cancer-specific circulating Treg subtype: A paradigm shift in single-cell immunology and its clinical implications.Clinical and translational medicine · 2026Article
- GPSM1 restricts CD73Nature communications · 2026Article
- [Clinical application value of sST2 in patients with heart failure].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Review
- Obesity disrupts ILC2 metabolic and functional homeostasis by inhibiting mTORC1 signaling.Cellular & molecular immunology · 2026Article
- Context-dependent roles of sex hormone signaling in controlling visceral adipose tissue Treg heterogeneity and clonal expansion.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- CD73 overexpression in ADSCs accelerates bladder repair by regulating the NFκB/NLRP3/caspase-1 signaling axis in neurogenic bladder rats.NPJ Regenerative medicine · 2026Article
- Targeting the heart-immune axis after myocardial infarction: from inflammation to immunomodulation.Frontiers in cardiovascular medicine · 2026Review
- The DBC1-HIF-1α-PPAR-γ axis regulates Treg cell differentiation to promote myocardial fibrosis in experimental diabetic cardiomyopathy through the paracrine secretion of Areg.Frontiers in endocrinology · 2026Article
- MiR-30d-5p Modulates Glucose and Lipid Metabolism by Targeting CD73 through the AMPK Pathway.Cell biochemistry and biophysics · 2025Article
- Nardilysin in adipocyte regulates insulin sensitivity via HIF1α and PPARγ.Scientific reports · 2025Article
- Adipose tissue ageing: implications for metabolic health and lifespan.Nature reviews. Endocrinology · 2025Review
- Regulatory T cells in brown adipose tissue safeguard thermogenesis by restraining interferon-γ-producing lymphocytes.Science immunology · 2025Article
- [Curcumin inhibits lipid metabolism in non-small cell lung cancer by downregulating the HIF-1α pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Gut Microbiota-Butyrate-PPARγ Axis Modulates Adipose Regulatory T Cell Population.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Tissue-Resident Regulatory T Cells Expressing CD83 Maintain Local Homeostasis and Restrict Th2 Responses in Asthma.European journal of immunology · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
22 authors at 5 institutions in 2 countries.
Yangyang Li *Department of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-5791-9443
Ying Lu *Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-3545-1026
Shu-Hai LinDepartment of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ning LiDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yichao HanDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-9691-3028
Qianru HuangDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi ZhaoDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feng XieDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yixian GuoDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Biaolong DengDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Andy TsunDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Juan DuDepartment of Pulmonary and Critical Care Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dan LiDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Joanne SunBiotheus Inc, Zhuhai, China.
Guochao ShiDepartment of Pulmonary and Critical Care Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fang ZhengDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiao SuUnit of Respiratory Infection and Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Shengzhong DuanLaboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Song Guo ZhengDepartment of Clinical Immunology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Gang WangState Key Laboratory of Genetic Engineering, School of Life Sciences and Zhongshan Hospital, Fudan University, Shanghai, China. gwang_fd@fudan.edu.cn.ORCID http://orcid.org/0000-0002-4582-501X
Xuemei TongDepartment of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. xuemeitong@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-2127-2019
Bin LiDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. binli@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-7640-8884
Shanghai Jiao Tong University · CNChinese Academy of Sciences · CNFudan University · CNHuazhong University of Science and Technology · CNSun Yat-sen University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systematic characterizations of adipose regulatory T (T
Indexed as
5'-NucleotidaseAdipose TissueAgingAnimalsCells, CulturedHigh-Throughput Nucleotide SequencingHypoxia-Inducible Factor 1, alpha SubunitInsulinInsulin ResistanceInterleukin-1 Receptor-Like 1 ProteinMaleMediator ComplexMiceMice, Inbred C57BLObesityPPAR gamma5'-NucleotidaseHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitIl1rl1 protein, mouseInsulinInterleukin-1 Receptor-Like 1 ProteinMed23 protein, mouseMediator ComplexPPAR gammaPparg protein, mouseReceptor, InsulinReceptors, Antigen, T-Cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.